Spexin-Based Galanin Receptor Type 2 Agonist for Comorbid Mood Disorders and Abnormal Body Weight

Spexin-Based Galanin Receptor Type 2 Agonist for Comorbid Mood Disorders and Abnormal Body Weight

Despite the established comorbidity between mood disorders and abnormal eating behaviors, the underlying molecular mechanism and therapeutics remain to be resolved. Here, we show that a spexin-based galanin receptor type 2 agonist (SG2A) simultaneously normalized mood behaviors and body weight in co...

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Bibliographic Details
Main Authors: Seongsik Yun, Arfaxad Reyes-Alcaraz, Yoo-Na Lee, Hyo Jeong Yong, Jeewon Choi, Byung-Joo Ham, Jong-Woo Sohn, Dong-Hoon Kim, Gi Hoon Son, Hyun Kim, Soon-Gu Kwon, Dong Sik Kim, Bong Chul Kim, Jong-Ik Hwang, Jae Young Seong
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-04-01
Series:Frontiers in Neuroscience
Subjects:
galanin receptor 2 agonist
depression
post-traumatic stress disorder
body weight
appetite
intranasal administration
Online Access:https://www.frontiersin.org/article/10.3389/fnins.2019.00391/full

Internet

https://www.frontiersin.org/article/10.3389/fnins.2019.00391/full

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