Small Cell Carcinoma of the Larynx Treated by Concurrent Chemoradiotherapy: A Case Report

Small Cell Carcinoma of the Larynx Treated by Concurrent Chemoradiotherapy: A Case Report

Small cell carcinoma (SmCC) generally occurs in the lung and extrapulmonary SmCC is a relatively rare entity. Here, we present a case of a 42-year-old male with SmCC of the larynx diagnosed as cT3N0M0. Concurrent chemoradiotherapy using cisplatin (CDDP) and etoposide (VP-16) was given, which achie...

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Main Authors: Susumu Nakahara, Norihiko Takemoto, Hidenori Inohara
Format: Article
Language:English
Published: Hindawi Limited 2012-01-01
Series:Case Reports in Otolaryngology
Online Access:http://dx.doi.org/10.1155/2012/316165
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spelling doaj-3bd76a18718d4c5c89991b7a2b70face2020-11-24T22:00:24ZengHindawi LimitedCase Reports in Otolaryngology2090-67652090-67732012-01-01201210.1155/2012/316165316165Small Cell Carcinoma of the Larynx Treated by Concurrent Chemoradiotherapy: A Case ReportSusumu Nakahara0Norihiko Takemoto1Hidenori Inohara2Department of Otorhinolaryngology-Head and Neck Surgery, Osaka University Graduate School of Medicine, 2-2 Yamadaoka, Suita, Osaka 565-0871, JapanDepartment of Otolaryngology, Suita Municipal Hospital, 2-13-20 Katayama, Suita, Osaka 564-0082, JapanDepartment of Otorhinolaryngology-Head and Neck Surgery, Osaka University Graduate School of Medicine, 2-2 Yamadaoka, Suita, Osaka 565-0871, JapanSmall cell carcinoma (SmCC) generally occurs in the lung and extrapulmonary SmCC is a relatively rare entity. Here, we present a case of a 42-year-old male with SmCC of the larynx diagnosed as cT3N0M0. Concurrent chemoradiotherapy using cisplatin (CDDP) and etoposide (VP-16) was given, which achieved complete response (CR). Lung metastasis became evident in 16 months whereas the locoregional control remained good. In spite of intensive chemotherapy using CDDP and irinotecan (CPT-11), the patient died of disease in 34 months after the first interview. Since the prognosis of laryngeal SmCC is extremely poor, organ preservation therapy should be considered instead of radical laryngectomy.http://dx.doi.org/10.1155/2012/316165
collection DOAJ
language English
format Article
sources DOAJ
author Susumu Nakahara
Norihiko Takemoto
Hidenori Inohara
spellingShingle Susumu Nakahara
Norihiko Takemoto
Hidenori Inohara
Small Cell Carcinoma of the Larynx Treated by Concurrent Chemoradiotherapy: A Case Report
Case Reports in Otolaryngology
author_facet Susumu Nakahara
Norihiko Takemoto
Hidenori Inohara
author_sort Susumu Nakahara
title Small Cell Carcinoma of the Larynx Treated by Concurrent Chemoradiotherapy: A Case Report
title_short Small Cell Carcinoma of the Larynx Treated by Concurrent Chemoradiotherapy: A Case Report
title_full Small Cell Carcinoma of the Larynx Treated by Concurrent Chemoradiotherapy: A Case Report
title_fullStr Small Cell Carcinoma of the Larynx Treated by Concurrent Chemoradiotherapy: A Case Report
title_full_unstemmed Small Cell Carcinoma of the Larynx Treated by Concurrent Chemoradiotherapy: A Case Report
title_sort small cell carcinoma of the larynx treated by concurrent chemoradiotherapy: a case report
publisher Hindawi Limited
series Case Reports in Otolaryngology
issn 2090-6765
2090-6773
publishDate 2012-01-01
description Small cell carcinoma (SmCC) generally occurs in the lung and extrapulmonary SmCC is a relatively rare entity. Here, we present a case of a 42-year-old male with SmCC of the larynx diagnosed as cT3N0M0. Concurrent chemoradiotherapy using cisplatin (CDDP) and etoposide (VP-16) was given, which achieved complete response (CR). Lung metastasis became evident in 16 months whereas the locoregional control remained good. In spite of intensive chemotherapy using CDDP and irinotecan (CPT-11), the patient died of disease in 34 months after the first interview. Since the prognosis of laryngeal SmCC is extremely poor, organ preservation therapy should be considered instead of radical laryngectomy.
url http://dx.doi.org/10.1155/2012/316165
work_keys_str_mv AT susumunakahara smallcellcarcinomaofthelarynxtreatedbyconcurrentchemoradiotherapyacasereport
AT norihikotakemoto smallcellcarcinomaofthelarynxtreatedbyconcurrentchemoradiotherapyacasereport
AT hidenoriinohara smallcellcarcinomaofthelarynxtreatedbyconcurrentchemoradiotherapyacasereport
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