ZFP57 regulation of transposable elements and gene expression within and beyond imprinted domains

ZFP57 regulation of transposable elements and gene expression within and beyond imprinted domains

Abstract Background KRAB zinc finger proteins (KZFPs) represent one of the largest families of DNA-binding proteins in vertebrate genomes and appear to have evolved to silence transposable elements (TEs) including endogenous retroviruses through sequence-specific targeting of repressive chromatin st...

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Bibliographic Details
Main Authors: Hui Shi, Ruslan Strogantsev, Nozomi Takahashi, Anastasiya Kazachenka, Matthew C. Lorincz, Myriam Hemberger, Anne C. Ferguson-Smith
Format: Article
Language:English
Published: BMC 2019-08-01
Series:Epigenetics & Chromatin
Subjects:
DNA methylation
KZFPs
ZFP57
Transposable elements
Embryonic stem cells
Online Access:http://link.springer.com/article/10.1186/s13072-019-0295-4

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