Alternative splicing in the differentiation of human embryonic stem cells into cardiac precursors.

Alternative splicing in the differentiation of human embryonic stem cells into cardiac precursors.

The role of alternative splicing in self-renewal, pluripotency and tissue lineage specification of human embryonic stem cells (hESCs) is largely unknown. To better define these regulatory cues, we modified the H9 hESC line to allow selection of pluripotent hESCs by neomycin resistance and cardiac pr...

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Bibliographic Details
Main Authors: Nathan Salomonis, Brandon Nelson, Karen Vranizan, Alexander R Pico, Kristina Hanspers, Allan Kuchinsky, Linda Ta, Mark Mercola, Bruce R Conklin
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-11-01
Series:PLoS Computational Biology
Online Access:http://europepmc.org/articles/PMC2764345?pdf=render

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