Structure of the plastic-degrading Ideonella sakaiensis MHETase bound to a substrate

Plastic polymer PET degrading enzymes are of great interest for achieving sustainable plastics recycling. Here, the authors present the crystal structures of the plastic degrading bacterial enzymes PETase, MHETase in its apo-form and MHETase bound to a non-hydrolyzable substrate analog.

Bibliographic Details
Main Authors:	Gottfried J. Palm, Lukas Reisky, Dominique Böttcher, Henrik Müller, Emil A. P. Michels, Miriam C. Walczak, Leona Berndt, Manfred S. Weiss, Uwe T. Bornscheuer, Gert Weber
Format:	Article
Language:	English
Published:	Nature Publishing Group 2019-04-01
Series:	Nature Communications
Online Access:	https://doi.org/10.1038/s41467-019-09326-3

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spelling	doaj-3bfbe70201754b2faf121427cc3babeb2021-05-11T12:16:30ZengNature Publishing GroupNature Communications2041-17232019-04-0110111010.1038/s41467-019-09326-3Structure of the plastic-degrading Ideonella sakaiensis MHETase bound to a substrateGottfried J. Palm0Lukas Reisky1Dominique Böttcher2Henrik Müller3Emil A. P. Michels4Miriam C. Walczak5Leona Berndt6Manfred S. Weiss7Uwe T. Bornscheuer8Gert Weber9Molecular Structural Biology, University of GreifswaldBiotechnology & Enzyme Catalysis, University of GreifswaldBiotechnology & Enzyme Catalysis, University of GreifswaldBiotechnology & Enzyme Catalysis, University of GreifswaldMolecular Structural Biology, University of GreifswaldBiotechnology & Enzyme Catalysis, University of GreifswaldMolecular Structural Biology, University of GreifswaldMacromolecular Crystallography, Helmholtz-Zentrum Berlin für Materialien und EnergieBiotechnology & Enzyme Catalysis, University of GreifswaldMolecular Structural Biology, University of GreifswaldPlastic polymer PET degrading enzymes are of great interest for achieving sustainable plastics recycling. Here, the authors present the crystal structures of the plastic degrading bacterial enzymes PETase, MHETase in its apo-form and MHETase bound to a non-hydrolyzable substrate analog.https://doi.org/10.1038/s41467-019-09326-3
collection	DOAJ
language	English
format	Article
sources	DOAJ
author	Gottfried J. Palm Lukas Reisky Dominique Böttcher Henrik Müller Emil A. P. Michels Miriam C. Walczak Leona Berndt Manfred S. Weiss Uwe T. Bornscheuer Gert Weber
spellingShingle	Gottfried J. Palm Lukas Reisky Dominique Böttcher Henrik Müller Emil A. P. Michels Miriam C. Walczak Leona Berndt Manfred S. Weiss Uwe T. Bornscheuer Gert Weber Structure of the plastic-degrading Ideonella sakaiensis MHETase bound to a substrate Nature Communications
author_facet	Gottfried J. Palm Lukas Reisky Dominique Böttcher Henrik Müller Emil A. P. Michels Miriam C. Walczak Leona Berndt Manfred S. Weiss Uwe T. Bornscheuer Gert Weber
author_sort	Gottfried J. Palm
title	Structure of the plastic-degrading Ideonella sakaiensis MHETase bound to a substrate
title_short	Structure of the plastic-degrading Ideonella sakaiensis MHETase bound to a substrate
title_full	Structure of the plastic-degrading Ideonella sakaiensis MHETase bound to a substrate
title_fullStr	Structure of the plastic-degrading Ideonella sakaiensis MHETase bound to a substrate
title_full_unstemmed	Structure of the plastic-degrading Ideonella sakaiensis MHETase bound to a substrate
title_sort	structure of the plastic-degrading ideonella sakaiensis mhetase bound to a substrate
publisher	Nature Publishing Group
series	Nature Communications
issn	2041-1723
publishDate	2019-04-01
description	Plastic polymer PET degrading enzymes are of great interest for achieving sustainable plastics recycling. Here, the authors present the crystal structures of the plastic degrading bacterial enzymes PETase, MHETase in its apo-form and MHETase bound to a non-hydrolyzable substrate analog.
url	https://doi.org/10.1038/s41467-019-09326-3
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Structure of the plastic-degrading Ideonella sakaiensis MHETase bound to a substrate

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