MELPHALAN-INDUCED CYTOTOXICITY IN THE BONE MARROW OF RATS BY FLOW CYTOMETRY MEASUREMENTS

MELPHALAN-INDUCED CYTOTOXICITY IN THE BONE MARROW OF RATS BY FLOW CYTOMETRY MEASUREMENTS

Background. Bone marrow (BM) that contains hematopoietic cells of various lineages is a sensitive target for a number of cytotoxic agents including chemotherapy drugs. Objective. Flow cytometry (FCM) was chosen to test cytotoxicity in BM of rats, that received melphalan either intravenously (i.v....

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Bibliographic Details
Main Authors: B I. Gerashchenko, I. M. Todor, O. O. Shevchuk, V. G. Nikolaev
Format: Article
Language:English
Published: Ukrmedknyha 2019-03-01
Series:International Journal of Medicine and Medical Research
Subjects:
bone marrow
melphalan
cytotoxicity
flow cytometry
polychromatic erythrocytes
total nucleated cells
Online Access:https://ojs.tdmu.edu.ua/index.php/ijmr/article/view/9836

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