Arterial stiffness and albuminuria as markers of endothelial dysfunction in those with chronic obstructive pulmonary disease
The objective: to assess the state of arterial stiffness and the level of albuminuria in patients with chronic obstructive pulmonary disease (COPD) and to investigate the presence and nature of the association of the studied parameters with clinical and laboratory parameters of COPD.Subjects and met...
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NEW TERRA Publishing House
2021-04-01
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doaj-3c07658b8c774202836da69ed8e5b2fa2021-07-28T20:57:50ZrusNEW TERRA Publishing HouseTuberkulez i Bolezni Lëgkih2075-12302542-15062021-04-01993344010.21292/2075-1230-2021-99-3-34-401517Arterial stiffness and albuminuria as markers of endothelial dysfunction in those with chronic obstructive pulmonary diseaseA. A. Bakina0V. A. Pavlenko1S. V. Naryshkina2Amur State Medical AcademyAmur State Medical AcademyAmur State Medical AcademyThe objective: to assess the state of arterial stiffness and the level of albuminuria in patients with chronic obstructive pulmonary disease (COPD) and to investigate the presence and nature of the association of the studied parameters with clinical and laboratory parameters of COPD.Subjects and methods. 70 patients with COPD were examined, they all were divided into 4 groups depending on severity of clinical symptoms and number of exacerbations suffered in the previous 12 months. Additionally to standard examinations, albuminuria level, the pulse wave velocity in aorta (PWVa), and cardio-ankle vascular index (CAVI) were assessed.Results. The increased albuminuria level was registered in 51.4% of patients mainly suffering from frequent exacerbations. The increased CAVI and PWVa also prevailed in individuals with a high frequency of exacerbation and their higher levels were found in 37.1% and 14.3% of patients, respectively. PWVa and CAVI values were found to be associated with albuminuria level and clinical and laboratory parameters of COPD.https://www.tibl-journal.com/jour/article/view/1520chronic obstructive pulmonary diseasearterial stiffnessendothelial dysfunctionalbuminuriainflammation |
collection |
DOAJ |
language |
Russian |
format |
Article |
sources |
DOAJ |
author |
A. A. Bakina V. A. Pavlenko S. V. Naryshkina |
spellingShingle |
A. A. Bakina V. A. Pavlenko S. V. Naryshkina Arterial stiffness and albuminuria as markers of endothelial dysfunction in those with chronic obstructive pulmonary disease Tuberkulez i Bolezni Lëgkih chronic obstructive pulmonary disease arterial stiffness endothelial dysfunction albuminuria inflammation |
author_facet |
A. A. Bakina V. A. Pavlenko S. V. Naryshkina |
author_sort |
A. A. Bakina |
title |
Arterial stiffness and albuminuria as markers of endothelial dysfunction in those with chronic obstructive pulmonary disease |
title_short |
Arterial stiffness and albuminuria as markers of endothelial dysfunction in those with chronic obstructive pulmonary disease |
title_full |
Arterial stiffness and albuminuria as markers of endothelial dysfunction in those with chronic obstructive pulmonary disease |
title_fullStr |
Arterial stiffness and albuminuria as markers of endothelial dysfunction in those with chronic obstructive pulmonary disease |
title_full_unstemmed |
Arterial stiffness and albuminuria as markers of endothelial dysfunction in those with chronic obstructive pulmonary disease |
title_sort |
arterial stiffness and albuminuria as markers of endothelial dysfunction in those with chronic obstructive pulmonary disease |
publisher |
NEW TERRA Publishing House |
series |
Tuberkulez i Bolezni Lëgkih |
issn |
2075-1230 2542-1506 |
publishDate |
2021-04-01 |
description |
The objective: to assess the state of arterial stiffness and the level of albuminuria in patients with chronic obstructive pulmonary disease (COPD) and to investigate the presence and nature of the association of the studied parameters with clinical and laboratory parameters of COPD.Subjects and methods. 70 patients with COPD were examined, they all were divided into 4 groups depending on severity of clinical symptoms and number of exacerbations suffered in the previous 12 months. Additionally to standard examinations, albuminuria level, the pulse wave velocity in aorta (PWVa), and cardio-ankle vascular index (CAVI) were assessed.Results. The increased albuminuria level was registered in 51.4% of patients mainly suffering from frequent exacerbations. The increased CAVI and PWVa also prevailed in individuals with a high frequency of exacerbation and their higher levels were found in 37.1% and 14.3% of patients, respectively. PWVa and CAVI values were found to be associated with albuminuria level and clinical and laboratory parameters of COPD. |
topic |
chronic obstructive pulmonary disease arterial stiffness endothelial dysfunction albuminuria inflammation |
url |
https://www.tibl-journal.com/jour/article/view/1520 |
work_keys_str_mv |
AT aabakina arterialstiffnessandalbuminuriaasmarkersofendothelialdysfunctioninthosewithchronicobstructivepulmonarydisease AT vapavlenko arterialstiffnessandalbuminuriaasmarkersofendothelialdysfunctioninthosewithchronicobstructivepulmonarydisease AT svnaryshkina arterialstiffnessandalbuminuriaasmarkersofendothelialdysfunctioninthosewithchronicobstructivepulmonarydisease |
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1721263917597982720 |