Neonatal Outcomes in Pregnant Women Infected with COVID-19 in Babol, North of Iran: A Retrospective Study with Short-Term Follow-Up
During the coronavirus disease 2019 (COVID-19) pandemic, the number of pregnant women and neonates suffering from COVID-19 increased. However, there is a lack of evidence on clinical characteristics and neonatal outcomes in pregnant women with COVID-19. We evaluated short-term outcomes (4 weeks post...
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doaj-3c23b487d54e463bb0bf44b29966a4232021-06-14T00:17:09ZengHindawi LimitedInfectious Diseases in Obstetrics and Gynecology1098-09972021-01-01202110.1155/2021/9952701Neonatal Outcomes in Pregnant Women Infected with COVID-19 in Babol, North of Iran: A Retrospective Study with Short-Term Follow-UpZahra Akbarian-Rad0Mohsen Haghshenas Mojaveri1Zinatossadat Bouzari2Farzin Sadeghi3Yousef Yahyapour4Mojgan Naeimi Rad5Somayeh Alizadeh6Soheil Ebrahimpour7Mahdi Sepidarkish8Mostafa Javanian9Non-Communicable Pediatric Disease Research CenterNon-Communicable Pediatric Disease Research CenterDepartment of Obstetrics & GynecologyCellular and Molecular Biology Research CenterInfectious Diseases and Tropical Medicine Research CenterClinical Research Development CenterClinical Research Development CenterInfectious Diseases and Tropical Medicine Research CenterDepartment of Biostatistics and EpidemiologyInfectious Diseases and Tropical Medicine Research CenterDuring the coronavirus disease 2019 (COVID-19) pandemic, the number of pregnant women and neonates suffering from COVID-19 increased. However, there is a lack of evidence on clinical characteristics and neonatal outcomes in pregnant women with COVID-19. We evaluated short-term outcomes (4 weeks postdischarge) and symptoms in neonates born to mothers infected with COVID-19. In this retrospective cohort study, we included all neonates born to pregnant women with COVID-19 admitted to Ayatollah Rohani Hospital, Babol, Iran, from February 10 to May 20, 2020. Clinical features, treatments, and neonatal outcomes were measured. Eight neonates were included in the current study. The mean gestational age and birth weight of newborns were 37±3.19 weeks (30₊6-40) and 3077.50±697.64 gr (1720-3900), respectively. Apgar score of the first and fifth minutes in all neonates was ≥8 and ≥9 out of 10, respectively. The most clinical presentations in symptomatic neonates were respiratory distress, tachypnea, vomiting, and feeding intolerance. This manifestation and high levels of serum C-reactive protein (CRP) in three infants are common in neonatal sepsis. The blood culture in all of them was negative. They have been successfully treated with our standard treatment. Our pregnant women showed a pattern of clinical characteristics and laboratory results similar to those described for nonpregnant COVID-19 infection. This study found no evidence of intrauterine or peripartum transmission of COVID-19 from mother to her child. Furthermore, the long-term outcomes of neonates need more study.http://dx.doi.org/10.1155/2021/9952701 |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Zahra Akbarian-Rad Mohsen Haghshenas Mojaveri Zinatossadat Bouzari Farzin Sadeghi Yousef Yahyapour Mojgan Naeimi Rad Somayeh Alizadeh Soheil Ebrahimpour Mahdi Sepidarkish Mostafa Javanian |
spellingShingle |
Zahra Akbarian-Rad Mohsen Haghshenas Mojaveri Zinatossadat Bouzari Farzin Sadeghi Yousef Yahyapour Mojgan Naeimi Rad Somayeh Alizadeh Soheil Ebrahimpour Mahdi Sepidarkish Mostafa Javanian Neonatal Outcomes in Pregnant Women Infected with COVID-19 in Babol, North of Iran: A Retrospective Study with Short-Term Follow-Up Infectious Diseases in Obstetrics and Gynecology |
author_facet |
Zahra Akbarian-Rad Mohsen Haghshenas Mojaveri Zinatossadat Bouzari Farzin Sadeghi Yousef Yahyapour Mojgan Naeimi Rad Somayeh Alizadeh Soheil Ebrahimpour Mahdi Sepidarkish Mostafa Javanian |
author_sort |
Zahra Akbarian-Rad |
title |
Neonatal Outcomes in Pregnant Women Infected with COVID-19 in Babol, North of Iran: A Retrospective Study with Short-Term Follow-Up |
title_short |
Neonatal Outcomes in Pregnant Women Infected with COVID-19 in Babol, North of Iran: A Retrospective Study with Short-Term Follow-Up |
title_full |
Neonatal Outcomes in Pregnant Women Infected with COVID-19 in Babol, North of Iran: A Retrospective Study with Short-Term Follow-Up |
title_fullStr |
Neonatal Outcomes in Pregnant Women Infected with COVID-19 in Babol, North of Iran: A Retrospective Study with Short-Term Follow-Up |
title_full_unstemmed |
Neonatal Outcomes in Pregnant Women Infected with COVID-19 in Babol, North of Iran: A Retrospective Study with Short-Term Follow-Up |
title_sort |
neonatal outcomes in pregnant women infected with covid-19 in babol, north of iran: a retrospective study with short-term follow-up |
publisher |
Hindawi Limited |
series |
Infectious Diseases in Obstetrics and Gynecology |
issn |
1098-0997 |
publishDate |
2021-01-01 |
description |
During the coronavirus disease 2019 (COVID-19) pandemic, the number of pregnant women and neonates suffering from COVID-19 increased. However, there is a lack of evidence on clinical characteristics and neonatal outcomes in pregnant women with COVID-19. We evaluated short-term outcomes (4 weeks postdischarge) and symptoms in neonates born to mothers infected with COVID-19. In this retrospective cohort study, we included all neonates born to pregnant women with COVID-19 admitted to Ayatollah Rohani Hospital, Babol, Iran, from February 10 to May 20, 2020. Clinical features, treatments, and neonatal outcomes were measured. Eight neonates were included in the current study. The mean gestational age and birth weight of newborns were 37±3.19 weeks (30₊6-40) and 3077.50±697.64 gr (1720-3900), respectively. Apgar score of the first and fifth minutes in all neonates was ≥8 and ≥9 out of 10, respectively. The most clinical presentations in symptomatic neonates were respiratory distress, tachypnea, vomiting, and feeding intolerance. This manifestation and high levels of serum C-reactive protein (CRP) in three infants are common in neonatal sepsis. The blood culture in all of them was negative. They have been successfully treated with our standard treatment. Our pregnant women showed a pattern of clinical characteristics and laboratory results similar to those described for nonpregnant COVID-19 infection. This study found no evidence of intrauterine or peripartum transmission of COVID-19 from mother to her child. Furthermore, the long-term outcomes of neonates need more study. |
url |
http://dx.doi.org/10.1155/2021/9952701 |
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