Parental relatedness through time revealed by runs of homozygosity in ancient DNA

Parental relatedness through time revealed by runs of homozygosity in ancient DNA

Little is known about how human parental relatedness varied across ancient populations. Runs of homozygosity (ROH) in the offspring’s genome can give clues. Here, the authors present a method to identify ROH in ancient genomes and infer low rates of close kin unions across most ancient populations....

Full description

Bibliographic Details
Main Authors: Harald Ringbauer, John Novembre, Matthias Steinrücken
Format: Article
Language:English
Published: Nature Publishing Group 2021-09-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-021-25289-w
id doaj-3c375c21a4024b49900aa78e6f0bd1ef
record_format Article
spelling doaj-3c375c21a4024b49900aa78e6f0bd1ef2021-09-19T11:49:17ZengNature Publishing GroupNature Communications2041-17232021-09-0112111110.1038/s41467-021-25289-wParental relatedness through time revealed by runs of homozygosity in ancient DNAHarald Ringbauer0John Novembre1Matthias Steinrücken2Department of Archaeogenetics, Max Planck Institute for Evolutionary AnthropologyDepartment of Human Genetics, University of ChicagoDepartment of Human Genetics, University of ChicagoLittle is known about how human parental relatedness varied across ancient populations. Runs of homozygosity (ROH) in the offspring’s genome can give clues. Here, the authors present a method to identify ROH in ancient genomes and infer low rates of close kin unions across most ancient populations.https://doi.org/10.1038/s41467-021-25289-w
collection DOAJ
language English
format Article
sources DOAJ
author Harald Ringbauer
John Novembre
Matthias Steinrücken
spellingShingle Harald Ringbauer
John Novembre
Matthias Steinrücken
Parental relatedness through time revealed by runs of homozygosity in ancient DNA
Nature Communications
author_facet Harald Ringbauer
John Novembre
Matthias Steinrücken
author_sort Harald Ringbauer
title Parental relatedness through time revealed by runs of homozygosity in ancient DNA
title_short Parental relatedness through time revealed by runs of homozygosity in ancient DNA
title_full Parental relatedness through time revealed by runs of homozygosity in ancient DNA
title_fullStr Parental relatedness through time revealed by runs of homozygosity in ancient DNA
title_full_unstemmed Parental relatedness through time revealed by runs of homozygosity in ancient DNA
title_sort parental relatedness through time revealed by runs of homozygosity in ancient dna
publisher Nature Publishing Group
series Nature Communications
issn 2041-1723
publishDate 2021-09-01
description Little is known about how human parental relatedness varied across ancient populations. Runs of homozygosity (ROH) in the offspring’s genome can give clues. Here, the authors present a method to identify ROH in ancient genomes and infer low rates of close kin unions across most ancient populations.
url https://doi.org/10.1038/s41467-021-25289-w
work_keys_str_mv AT haraldringbauer parentalrelatednessthroughtimerevealedbyrunsofhomozygosityinancientdna
AT johnnovembre parentalrelatednessthroughtimerevealedbyrunsofhomozygosityinancientdna
AT matthiassteinrucken parentalrelatednessthroughtimerevealedbyrunsofhomozygosityinancientdna
_version_ 1717375474167971840

Similar Items