SNPs Array Karyotyping in Non-Hodgkin Lymphoma

SNPs Array Karyotyping in Non-Hodgkin Lymphoma

The traditional methods for detection of chromosomal aberrations, which included cytogenetic or gene candidate solutions, suffered from low sensitivity or the need for previous knowledge of the target regions of the genome. With the advent of single nucleotide polymorphism (SNP) arrays, genome scree...

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Main Authors: Maryam Etebari, Mohsen Navari, Pier Paolo Piccaluga
Format: Article
Language:English
Published: MDPI AG 2015-11-01
Series:Microarrays
Subjects:
non-Hodgkin lymphoma
single nucleotide polymorphism (SNP) array
genetic aberrations
Online Access:http://www.mdpi.com/2076-3905/4/4/551
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spelling doaj-3c445420e7094b25a2866160ca578caa2020-11-24T21:33:19ZengMDPI AGMicroarrays2076-39052015-11-014455156910.3390/microarrays4040551microarrays4040551SNPs Array Karyotyping in Non-Hodgkin LymphomaMaryam Etebari0Mohsen Navari1Pier Paolo Piccaluga2Department of Experimental, Diagnostic, and Specialty Medicine; Hematopathology Unit, S. Orsola-Malpighi Hospital, Bologna 40138, ItalyDepartment of Experimental, Diagnostic, and Specialty Medicine; Hematopathology Unit, S. Orsola-Malpighi Hospital, Bologna 40138, ItalyDepartment of Experimental, Diagnostic, and Specialty Medicine; Hematopathology Unit, S. Orsola-Malpighi Hospital, Bologna 40138, ItalyThe traditional methods for detection of chromosomal aberrations, which included cytogenetic or gene candidate solutions, suffered from low sensitivity or the need for previous knowledge of the target regions of the genome. With the advent of single nucleotide polymorphism (SNP) arrays, genome screening at global level in order to find chromosomal aberrations like copy number variants, DNA amplifications, deletions, and also loss of heterozygosity became feasible. In this review, we present an update of the knowledge, gained by SNPs arrays, of the genomic complexity of the most important subtypes of non-Hodgkin lymphomas.http://www.mdpi.com/2076-3905/4/4/551non-Hodgkin lymphomasingle nucleotide polymorphism (SNP) arraygenetic aberrations
collection DOAJ
language English
format Article
sources DOAJ
author Maryam Etebari
Mohsen Navari
Pier Paolo Piccaluga
spellingShingle Maryam Etebari
Mohsen Navari
Pier Paolo Piccaluga
SNPs Array Karyotyping in Non-Hodgkin Lymphoma
Microarrays
non-Hodgkin lymphoma
single nucleotide polymorphism (SNP) array
genetic aberrations
author_facet Maryam Etebari
Mohsen Navari
Pier Paolo Piccaluga
author_sort Maryam Etebari
title SNPs Array Karyotyping in Non-Hodgkin Lymphoma
title_short SNPs Array Karyotyping in Non-Hodgkin Lymphoma
title_full SNPs Array Karyotyping in Non-Hodgkin Lymphoma
title_fullStr SNPs Array Karyotyping in Non-Hodgkin Lymphoma
title_full_unstemmed SNPs Array Karyotyping in Non-Hodgkin Lymphoma
title_sort snps array karyotyping in non-hodgkin lymphoma
publisher MDPI AG
series Microarrays
issn 2076-3905
publishDate 2015-11-01
description The traditional methods for detection of chromosomal aberrations, which included cytogenetic or gene candidate solutions, suffered from low sensitivity or the need for previous knowledge of the target regions of the genome. With the advent of single nucleotide polymorphism (SNP) arrays, genome screening at global level in order to find chromosomal aberrations like copy number variants, DNA amplifications, deletions, and also loss of heterozygosity became feasible. In this review, we present an update of the knowledge, gained by SNPs arrays, of the genomic complexity of the most important subtypes of non-Hodgkin lymphomas.
topic non-Hodgkin lymphoma
single nucleotide polymorphism (SNP) array
genetic aberrations
url http://www.mdpi.com/2076-3905/4/4/551
work_keys_str_mv AT maryametebari snpsarraykaryotypinginnonhodgkinlymphoma
AT mohsennavari snpsarraykaryotypinginnonhodgkinlymphoma
AT pierpaolopiccaluga snpsarraykaryotypinginnonhodgkinlymphoma
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