Catechins within the Biopolymer Matrix—Design Concepts and Bioactivity Prospects

Epidemiological studies and clinical investigations proposed that catechins extracts alone may not provide a sufficient level of bioactivities and promising therapeutic effects to achieve health benefits due to a number of constraints related to poor oral absorption, limited bioavailability, sensiti...

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Main Authors: Zvezdelina Yaneva, Donika Ivanova
Format: Article
Language:English
Published: MDPI AG 2020-11-01
Series:Antioxidants
Subjects:
Online Access:https://www.mdpi.com/2076-3921/9/12/1180
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spelling doaj-3c45408d80ab498992e6ce589f3febdb2020-11-27T08:10:45ZengMDPI AGAntioxidants2076-39212020-11-0191180118010.3390/antiox9121180Catechins within the Biopolymer Matrix—Design Concepts and Bioactivity ProspectsZvezdelina Yaneva0Donika Ivanova1Chemistry Unit, Department of Pharmacology, Animal Physiology and Physiological Chemistry, Faculty of Veterinary Medicine, Trakia University, Students Campus, 6000 Stara Zagora, BulgariaChemistry Unit, Department of Pharmacology, Animal Physiology and Physiological Chemistry, Faculty of Veterinary Medicine, Trakia University, Students Campus, 6000 Stara Zagora, BulgariaEpidemiological studies and clinical investigations proposed that catechins extracts alone may not provide a sufficient level of bioactivities and promising therapeutic effects to achieve health benefits due to a number of constraints related to poor oral absorption, limited bioavailability, sensitivity to oxidation, etc. Modern scientific studies have reported numerous techniques for the design of micro- and nano-bio-delivery systems as novel and promising strategies to overcome these obstacles and to enhance catechins’ therapeutic activity. The objective assessment of their benefits, however, requires a critical comparative estimation of the advantages and disadvantages of the designed catechins-biocarrier systems, their biological activities and safety administration aspects. In this respect, the present review objectively outlines, compares and assesses the recent advances related to newly developed design concepts of catechins’ encapsulation into various biopolymer carriers and their release behaviour, with a special emphasis on the specific physiological biofunctionalities of the innovative bioflavonoid/biopolymer delivery systems.https://www.mdpi.com/2076-3921/9/12/1180catechinsbiopolymer formulationsencapsulationreleasebiological activity
collection DOAJ
language English
format Article
sources DOAJ
author Zvezdelina Yaneva
Donika Ivanova
spellingShingle Zvezdelina Yaneva
Donika Ivanova
Catechins within the Biopolymer Matrix—Design Concepts and Bioactivity Prospects
Antioxidants
catechins
biopolymer formulations
encapsulation
release
biological activity
author_facet Zvezdelina Yaneva
Donika Ivanova
author_sort Zvezdelina Yaneva
title Catechins within the Biopolymer Matrix—Design Concepts and Bioactivity Prospects
title_short Catechins within the Biopolymer Matrix—Design Concepts and Bioactivity Prospects
title_full Catechins within the Biopolymer Matrix—Design Concepts and Bioactivity Prospects
title_fullStr Catechins within the Biopolymer Matrix—Design Concepts and Bioactivity Prospects
title_full_unstemmed Catechins within the Biopolymer Matrix—Design Concepts and Bioactivity Prospects
title_sort catechins within the biopolymer matrix—design concepts and bioactivity prospects
publisher MDPI AG
series Antioxidants
issn 2076-3921
publishDate 2020-11-01
description Epidemiological studies and clinical investigations proposed that catechins extracts alone may not provide a sufficient level of bioactivities and promising therapeutic effects to achieve health benefits due to a number of constraints related to poor oral absorption, limited bioavailability, sensitivity to oxidation, etc. Modern scientific studies have reported numerous techniques for the design of micro- and nano-bio-delivery systems as novel and promising strategies to overcome these obstacles and to enhance catechins’ therapeutic activity. The objective assessment of their benefits, however, requires a critical comparative estimation of the advantages and disadvantages of the designed catechins-biocarrier systems, their biological activities and safety administration aspects. In this respect, the present review objectively outlines, compares and assesses the recent advances related to newly developed design concepts of catechins’ encapsulation into various biopolymer carriers and their release behaviour, with a special emphasis on the specific physiological biofunctionalities of the innovative bioflavonoid/biopolymer delivery systems.
topic catechins
biopolymer formulations
encapsulation
release
biological activity
url https://www.mdpi.com/2076-3921/9/12/1180
work_keys_str_mv AT zvezdelinayaneva catechinswithinthebiopolymermatrixdesignconceptsandbioactivityprospects
AT donikaivanova catechinswithinthebiopolymermatrixdesignconceptsandbioactivityprospects
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