A Combination Therapy of pHRE-Egr1-HSV-TK/Anti-CD133McAb-131I/MFH Mediated by FePt Nanoparticles for Liver Cancer Stem Cells

It has been evidenced that liver cancer stem cells (LCSCs) are to blame hepatocellular carcinoma (HCC) occurrence, development, metastasis, and recurrence. Using iron-platinum nanoparticles (FePt-NPs) as a carrier and CD133 antigen as a target, a new strategy to targetly kill LCSCs by integrating HS...

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Bibliographic Details
Main Authors: Mei Lin, Yanhong Xiao, Xingmao Jiang, Jun Zhang, Ting Guo, Yujuan Shi
Format: Article
Language:English
Published: Hindawi Limited 2020-01-01
Series:Journal of Nanomaterials
Online Access:http://dx.doi.org/10.1155/2020/7180613