A novel tandem reporter quantifies RNA polymerase II termination in mammalian cells.
Making the correct choice between transcription elongation and transcription termination is essential to the function of RNA polymerase II, and fundamental to gene expression. This choice can be influenced by factors modifying the transcription complex, factors modifying chromatin, or signals mediat...
Main Authors: | Ayan Banerjee, Mimi C Sammarco, Scott Ditch, Jeffrey Wang, Ed Grabczyk |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2009-07-01
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Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC2702688?pdf=render |
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