Intrapartum human immunodeficiency virus transmission rate in a central hospital in the Western Cape province after universal antiretroviral therapy roll-out

The national human immunodeficiency virus (HIV) mother-to-child transmission rate at 6–10 weeks post-partum was 0.9% in 2016. There is a paucity of data about the intrapartum transmission rate after lifelong antiretroviral therapy was implemented in 2015. We assessed all pregnant women living with H...

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Bibliographic Details
Main Authors: Tian A. van der Merwe, Gert U. van Zyl, Carl J. Lombard, Gerhard B. Theron
Format: Article
Language:English
Published: AOSIS 2020-12-01
Series:Southern African Journal of Infectious Diseases
Subjects:
hiv
Online Access:https://sajid.co.za/index.php/sajid/article/view/192
Description
Summary:The national human immunodeficiency virus (HIV) mother-to-child transmission rate at 6–10 weeks post-partum was 0.9% in 2016. There is a paucity of data about the intrapartum transmission rate after lifelong antiretroviral therapy was implemented in 2015. We assessed all pregnant women living with HIV who delivered at Tygerberg Hospital in 2017. Positive polymerase chain reactions (PCRs) at birth indicated an in utero transmission rate of 0.8%. One infant with a negative PCR at birth tested positive at 6–10 weeks. The intrapartum transmission rate was low (0.08%). About 25% of infants were lost to follow-up after birth.
ISSN:2312-0053
2313-1810