Intrapartum human immunodeficiency virus transmission rate in a central hospital in the Western Cape province after universal antiretroviral therapy roll-out
The national human immunodeficiency virus (HIV) mother-to-child transmission rate at 6–10 weeks post-partum was 0.9% in 2016. There is a paucity of data about the intrapartum transmission rate after lifelong antiretroviral therapy was implemented in 2015. We assessed all pregnant women living with H...
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2020-12-01
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| Series: | Southern African Journal of Infectious Diseases |
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| Online Access: | https://sajid.co.za/index.php/sajid/article/view/192 |
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doaj-3c5e2b44a021448194b85e17d07582e22020-12-11T13:59:18ZengAOSISSouthern African Journal of Infectious Diseases2312-00532313-18102020-12-01351e1e410.4102/sajid.v35i1.192158Intrapartum human immunodeficiency virus transmission rate in a central hospital in the Western Cape province after universal antiretroviral therapy roll-outTian A. van der Merwe0Gert U. van Zyl1Carl J. Lombard2Gerhard B. Theron3Department of Obstetrics and Gynaecology, Faculty of Medicine and Health Sciences, Stellenbosch University, Cape TownDivision of Medical Virology, Faculty of Medicine and Health Sciences, Stellenbosch University, Cape Town, South Africa; and National Health Laboratory Service, Tygerberg VirologyDivision of Epidemiology and Biostatistics, Department of Global Health, Stellenbosch University, Cape TownDepartment of Obstetrics and Gynaecology, Faculty of Medicine and Health Sciences, Stellenbosch University, Cape TownThe national human immunodeficiency virus (HIV) mother-to-child transmission rate at 6–10 weeks post-partum was 0.9% in 2016. There is a paucity of data about the intrapartum transmission rate after lifelong antiretroviral therapy was implemented in 2015. We assessed all pregnant women living with HIV who delivered at Tygerberg Hospital in 2017. Positive polymerase chain reactions (PCRs) at birth indicated an in utero transmission rate of 0.8%. One infant with a negative PCR at birth tested positive at 6–10 weeks. The intrapartum transmission rate was low (0.08%). About 25% of infants were lost to follow-up after birth.https://sajid.co.za/index.php/sajid/article/view/192human immunodeficiency virushivmothersbirthprevention of mother-to-child transmissionpmtctintrapartum. |
| collection |
DOAJ |
| language |
English |
| format |
Article |
| sources |
DOAJ |
| author |
Tian A. van der Merwe Gert U. van Zyl Carl J. Lombard Gerhard B. Theron |
| spellingShingle |
Tian A. van der Merwe Gert U. van Zyl Carl J. Lombard Gerhard B. Theron Intrapartum human immunodeficiency virus transmission rate in a central hospital in the Western Cape province after universal antiretroviral therapy roll-out Southern African Journal of Infectious Diseases human immunodeficiency virus hiv mothers birth prevention of mother-to-child transmission pmtct intrapartum. |
| author_facet |
Tian A. van der Merwe Gert U. van Zyl Carl J. Lombard Gerhard B. Theron |
| author_sort |
Tian A. van der Merwe |
| title |
Intrapartum human immunodeficiency virus transmission rate in a central hospital in the Western Cape province after universal antiretroviral therapy roll-out |
| title_short |
Intrapartum human immunodeficiency virus transmission rate in a central hospital in the Western Cape province after universal antiretroviral therapy roll-out |
| title_full |
Intrapartum human immunodeficiency virus transmission rate in a central hospital in the Western Cape province after universal antiretroviral therapy roll-out |
| title_fullStr |
Intrapartum human immunodeficiency virus transmission rate in a central hospital in the Western Cape province after universal antiretroviral therapy roll-out |
| title_full_unstemmed |
Intrapartum human immunodeficiency virus transmission rate in a central hospital in the Western Cape province after universal antiretroviral therapy roll-out |
| title_sort |
intrapartum human immunodeficiency virus transmission rate in a central hospital in the western cape province after universal antiretroviral therapy roll-out |
| publisher |
AOSIS |
| series |
Southern African Journal of Infectious Diseases |
| issn |
2312-0053 2313-1810 |
| publishDate |
2020-12-01 |
| description |
The national human immunodeficiency virus (HIV) mother-to-child transmission rate at 6–10 weeks post-partum was 0.9% in 2016. There is a paucity of data about the intrapartum transmission rate after lifelong antiretroviral therapy was implemented in 2015. We assessed all pregnant women living with HIV who delivered at Tygerberg Hospital in 2017. Positive polymerase chain reactions (PCRs) at birth indicated an in utero transmission rate of 0.8%. One infant with a negative PCR at birth tested positive at 6–10 weeks. The intrapartum transmission rate was low (0.08%). About 25% of infants were lost to follow-up after birth. |
| topic |
human immunodeficiency virus hiv mothers birth prevention of mother-to-child transmission pmtct intrapartum. |
| url |
https://sajid.co.za/index.php/sajid/article/view/192 |
| work_keys_str_mv |
AT tianavandermerwe intrapartumhumanimmunodeficiencyvirustransmissionrateinacentralhospitalinthewesterncapeprovinceafteruniversalantiretroviraltherapyrollout AT gertuvanzyl intrapartumhumanimmunodeficiencyvirustransmissionrateinacentralhospitalinthewesterncapeprovinceafteruniversalantiretroviraltherapyrollout AT carljlombard intrapartumhumanimmunodeficiencyvirustransmissionrateinacentralhospitalinthewesterncapeprovinceafteruniversalantiretroviraltherapyrollout AT gerhardbtheron intrapartumhumanimmunodeficiencyvirustransmissionrateinacentralhospitalinthewesterncapeprovinceafteruniversalantiretroviraltherapyrollout |
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