Molecular mechanisms of pancreatic stone formation in chronic pancreatitis.

Molecular mechanisms of pancreatic stone formation in chronic pancreatitis.

Chronic pancreatitis (CP) is a progressive inflammatory disease in which the pancreatic secretory parenchyma is destroyed and replaced by fibrosis. The presence of intraductal pancreatic stone(s) is important for the diagnosis of CP; however, the precise molecular mechanisms of pancreatic stone form...

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Bibliographic Details
Main Authors: Shigeru B.H. Ko, Sakiko eAzuma, Toshiyuki eYoshikawa, Akiko eYamamoto, Kazuhiro eKyokane, Minoru S.H. Ko, Hiroshi eIshiguro
Format: Article
Language:English
Published: Frontiers Media S.A. 2012-11-01
Series:Frontiers in Physiology
Subjects:
Chronic pancreatitis
bicarbonate secretion
CFTR
pancreatic stone formation
cytoplasmic mislocalization
Online Access:http://journal.frontiersin.org/Journal/10.3389/fphys.2012.00415/full

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