| Summary: | <p><strong>Purpose</strong>: to analyze clinical polymorphism of endocrine ophthalmopathy in patients with Graves’ disease.<br /><strong>Methods</strong>: Clinical and radiological data of 18 cases with clinical manifestations of lacrimal gland increase were analyzed and compared with data retrieved from 50 patients without increasing of lacrimal gland.<br /><strong>Results</strong>: the characteristics of clinical manifestations of endocrine ophthalmopathy with lacrimal gland increase were presented. this form differs, as the organ of the target, along with orbital fat and/or eye muscles becomes the glandula lacrimalis. A correlation between fact involving, on the one hand, and the intensity and severity of the autoimmune process in orbit, on the other hand were identified.<br /><strong>Conclusion</strong>: Involvement of this secretion organ in the autoimmune process makes the clinical course of endocrine ophthalmopa-<br />thy more complicated, and leads to eye dry syndrome creation.</p>
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