Magnesium Promotes the Regeneration of the Peripheral Nerve
Peripheral nerve injury is a common complication in trauma, and regeneration and function recovery are clinical challenges. It is indispensable to find a suitable material to promote peripheral nerve regeneration due to the limited capacity of peripheral nerve regeneration, which is not an easy task...
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doaj-3c96ac1fff4a4e34ade59320be073f132021-08-11T05:57:35ZengFrontiers Media S.A.Frontiers in Cell and Developmental Biology2296-634X2021-08-01910.3389/fcell.2021.717854717854Magnesium Promotes the Regeneration of the Peripheral NerveJingxin Zhang0Binjing Zhang1Jinglan Zhang2Weimin Lin3Shiwen Zhang4Shiwen Zhang5State Key Laboratory of Oral Diseases & National Clinical Research Center for Oral Diseases, West China Hospital of Stomatology, Sichuan University, Chengdu, ChinaState Key Laboratory of Oral Diseases & National Clinical Research Center for Oral Diseases, West China Hospital of Stomatology, Sichuan University, Chengdu, ChinaState Key Laboratory of Oral Diseases & National Clinical Research Center for Oral Diseases, West China Hospital of Stomatology, Sichuan University, Chengdu, ChinaState Key Laboratory of Oral Diseases & National Clinical Research Center for Oral Diseases, West China Hospital of Stomatology, Sichuan University, Chengdu, ChinaState Key Laboratory of Oral Diseases & National Clinical Research Center for Oral Diseases, West China Hospital of Stomatology, Sichuan University, Chengdu, ChinaDepartment of Oral Implantology, West China Hospital of Stomatology, Sichuan University, Chengdu, ChinaPeripheral nerve injury is a common complication in trauma, and regeneration and function recovery are clinical challenges. It is indispensable to find a suitable material to promote peripheral nerve regeneration due to the limited capacity of peripheral nerve regeneration, which is not an easy task to design a material with good biocompatibility, appropriate degradability. Magnesium has captured increasing attention during the past years as suitable materials. However, there are little types of research on magnesium promoting peripheral nerve regeneration. In this review, we conclude the possible mechanism of magnesium ion promoting peripheral nerve regeneration and the properties and application of different kinds of magnesium-based biomaterials, such as magnesium filaments, magnesium alloys, and others, in which we found some shortcomings and challenges. So, magnesium can promote peripheral nerve regeneration with both challenge and potential.https://www.frontiersin.org/articles/10.3389/fcell.2021.717854/fullperipheral nerve repairnerve regenerationmagnesiumbiodegradabilitybiocompatibility |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Jingxin Zhang Binjing Zhang Jinglan Zhang Weimin Lin Shiwen Zhang Shiwen Zhang |
spellingShingle |
Jingxin Zhang Binjing Zhang Jinglan Zhang Weimin Lin Shiwen Zhang Shiwen Zhang Magnesium Promotes the Regeneration of the Peripheral Nerve Frontiers in Cell and Developmental Biology peripheral nerve repair nerve regeneration magnesium biodegradability biocompatibility |
author_facet |
Jingxin Zhang Binjing Zhang Jinglan Zhang Weimin Lin Shiwen Zhang Shiwen Zhang |
author_sort |
Jingxin Zhang |
title |
Magnesium Promotes the Regeneration of the Peripheral Nerve |
title_short |
Magnesium Promotes the Regeneration of the Peripheral Nerve |
title_full |
Magnesium Promotes the Regeneration of the Peripheral Nerve |
title_fullStr |
Magnesium Promotes the Regeneration of the Peripheral Nerve |
title_full_unstemmed |
Magnesium Promotes the Regeneration of the Peripheral Nerve |
title_sort |
magnesium promotes the regeneration of the peripheral nerve |
publisher |
Frontiers Media S.A. |
series |
Frontiers in Cell and Developmental Biology |
issn |
2296-634X |
publishDate |
2021-08-01 |
description |
Peripheral nerve injury is a common complication in trauma, and regeneration and function recovery are clinical challenges. It is indispensable to find a suitable material to promote peripheral nerve regeneration due to the limited capacity of peripheral nerve regeneration, which is not an easy task to design a material with good biocompatibility, appropriate degradability. Magnesium has captured increasing attention during the past years as suitable materials. However, there are little types of research on magnesium promoting peripheral nerve regeneration. In this review, we conclude the possible mechanism of magnesium ion promoting peripheral nerve regeneration and the properties and application of different kinds of magnesium-based biomaterials, such as magnesium filaments, magnesium alloys, and others, in which we found some shortcomings and challenges. So, magnesium can promote peripheral nerve regeneration with both challenge and potential. |
topic |
peripheral nerve repair nerve regeneration magnesium biodegradability biocompatibility |
url |
https://www.frontiersin.org/articles/10.3389/fcell.2021.717854/full |
work_keys_str_mv |
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