Main Oral Manifestations in Immune-Mediated and Inflammatory Rheumatic Diseases
Oral manifestations are frequent in patients with rheumatic diseases. The aim of this review is to offer readers practical advice concerning the onset, diagnosis and treatment of the main oral manifestations encountered in rheumatological and dental clinics. Signs and symptoms such as oral hyposaliv...
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doaj-3ca276aa6cb94d75bcc7da189161472c2020-11-25T00:17:36ZengMDPI AGJournal of Clinical Medicine2077-03832018-12-01812110.3390/jcm8010021jcm8010021Main Oral Manifestations in Immune-Mediated and Inflammatory Rheumatic DiseasesRoberta Gualtierotti0Angelo Valerio Marzano1Francesco Spadari2Massimo Cugno3Department of Clinical Sciences and Community Health, Università degli Studi di Milano, 20122 Milano, ItalyDepartment of Pathophysiology and Transplantation, Università degli Studi di Milano, Dermatology Unit, IRCCS Fondazione Ca’ Granda, Ospedale Maggiore Policlinico, 20122 Milano, ItalyDepartment of Biomedical, Surgical and Dental Sciences, Università degli Studi di Milano, 20122 Milano, ItalyDepartment of Pathophysiology and Transplantation, Università degli Studi di Milano, Internal Medicine, IRCCS Fondazione Ca’ Granda, Ospedale Maggiore Policlinico, 20122 Milano, ItalyOral manifestations are frequent in patients with rheumatic diseases. The aim of this review is to offer readers practical advice concerning the onset, diagnosis and treatment of the main oral manifestations encountered in rheumatological and dental clinics. Signs and symptoms such as oral hyposalivation, xerostomia, temporomandibular joint disorders, periodontal disease, and dysphagia may be the first expression of a number of rheumatic diseases. Some of these manifestations are aspecific and very frequent, such as oral aphthosis, which can be the first manifestation in patients with systemic lupus erythematosus; some are potentially dangerous, such as jaw claudication during the course of giant cell arteritis; and some are very rare but peculiar, such as strawberry-like gingivitis in patients with granulomatosis with polyangiitis. Other oral manifestations are due to adverse reactions to disease-modifying anti-rheumatic drugs. Oral alterations in rheumatic diseases are frequently overlooked in clinical practice, but their prompt recognition not only allows the local lesions to be appropriately treated, but also makes it possible to identify an underlying systemic disease.http://www.mdpi.com/2077-0383/8/1/21rheumatoid arthritissystemic lupus erythematosusBehçet’s diseaseSjögren’s syndromeoral lesions |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Roberta Gualtierotti Angelo Valerio Marzano Francesco Spadari Massimo Cugno |
spellingShingle |
Roberta Gualtierotti Angelo Valerio Marzano Francesco Spadari Massimo Cugno Main Oral Manifestations in Immune-Mediated and Inflammatory Rheumatic Diseases Journal of Clinical Medicine rheumatoid arthritis systemic lupus erythematosus Behçet’s disease Sjögren’s syndrome oral lesions |
author_facet |
Roberta Gualtierotti Angelo Valerio Marzano Francesco Spadari Massimo Cugno |
author_sort |
Roberta Gualtierotti |
title |
Main Oral Manifestations in Immune-Mediated and Inflammatory Rheumatic Diseases |
title_short |
Main Oral Manifestations in Immune-Mediated and Inflammatory Rheumatic Diseases |
title_full |
Main Oral Manifestations in Immune-Mediated and Inflammatory Rheumatic Diseases |
title_fullStr |
Main Oral Manifestations in Immune-Mediated and Inflammatory Rheumatic Diseases |
title_full_unstemmed |
Main Oral Manifestations in Immune-Mediated and Inflammatory Rheumatic Diseases |
title_sort |
main oral manifestations in immune-mediated and inflammatory rheumatic diseases |
publisher |
MDPI AG |
series |
Journal of Clinical Medicine |
issn |
2077-0383 |
publishDate |
2018-12-01 |
description |
Oral manifestations are frequent in patients with rheumatic diseases. The aim of this review is to offer readers practical advice concerning the onset, diagnosis and treatment of the main oral manifestations encountered in rheumatological and dental clinics. Signs and symptoms such as oral hyposalivation, xerostomia, temporomandibular joint disorders, periodontal disease, and dysphagia may be the first expression of a number of rheumatic diseases. Some of these manifestations are aspecific and very frequent, such as oral aphthosis, which can be the first manifestation in patients with systemic lupus erythematosus; some are potentially dangerous, such as jaw claudication during the course of giant cell arteritis; and some are very rare but peculiar, such as strawberry-like gingivitis in patients with granulomatosis with polyangiitis. Other oral manifestations are due to adverse reactions to disease-modifying anti-rheumatic drugs. Oral alterations in rheumatic diseases are frequently overlooked in clinical practice, but their prompt recognition not only allows the local lesions to be appropriately treated, but also makes it possible to identify an underlying systemic disease. |
topic |
rheumatoid arthritis systemic lupus erythematosus Behçet’s disease Sjögren’s syndrome oral lesions |
url |
http://www.mdpi.com/2077-0383/8/1/21 |
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