The Helicobacter pylori Heat-Shock Repressor HspR: Definition of Its Direct Regulon and Characterization of the Cooperative DNA-Binding Mechanism on Its Own Promoter

The Helicobacter pylori Heat-Shock Repressor HspR: Definition of Its Direct Regulon and Characterization of the Cooperative DNA-Binding Mechanism on Its Own Promoter

The ability of pathogens to perceive environmental conditions and modulate gene expression accordingly is a crucial feature for bacterial survival. In this respect, the heat-shock response, a universal cellular response, allows cells to adapt to hostile environmental conditions and to survive during...

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Bibliographic Details
Main Authors: Simona Pepe, Eva Pinatel, Elisabetta Fiore, Simone Puccio, Clelia Peano, Tarcisio Brignoli, Andrea Vannini, Alberto Danielli, Vincenzo Scarlato, Davide Roncarati
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-08-01
Series:Frontiers in Microbiology
Subjects:
heat-shock response
HspR repressor
ChIP-seq
RNA-sequencing
transcriptome
Online Access:https://www.frontiersin.org/article/10.3389/fmicb.2018.01887/full

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