Age dependent differences in the kinetics of γδ T cells after influenza vaccination.
Immunosenescence is a hallmark of the aging immune system and is considered the main cause of a reduced vaccine efficacy in the elderly. Although γδ T cells can become activated by recombinant influenza hemagglutinin, their age-related immunocompetence during a virus-induced immune response has so f...
Main Authors: | Ulrik Stervbo, Dominika Pohlmann, Udo Baron, Cecilia Bozzetti, Karsten Jürchott, Julia Nora Mälzer, Mikalai Nienen, Sven Olek, Toralf Roch, Axel Ronald Schulz, Sarah Warth, Avidan Neumann, Andreas Thiel, Andreas Grützkau, Nina Babel |
---|---|
Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2017-01-01
|
Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC5507438?pdf=render |
Similar Items
-
Highly Predictive Model for a Protective Immune Response to the A(H1N1)pdm2009 Influenza Strain after Seasonal Vaccination.
by: Karsten Jürchott, et al.
Published: (2016-01-01) -
The Role of Pre-existing Cross-Reactive Central Memory CD4 T-Cells in Vaccination With Previously Unseen Influenza Strains
by: Mikalai Nienen, et al.
Published: (2019-04-01) -
BKV Clearance Time Correlates With Exhaustion State and T-Cell Receptor Repertoire Shape of BKV-Specific T-Cells in Renal Transplant Patients
by: Ulrik Stervbo, et al.
Published: (2019-04-01) -
SLAMF7 and IL-6R define distinct cytotoxic versus helper memory CD8+ T cells
by: Lucie Loyal, et al.
Published: (2020-12-01) -
Repeated Changes to the Gravitational Field Negatively Affect the Serum Concentration of Select Growth Factors and Cytokines
by: Ulrik Stervbo, et al.
Published: (2019-04-01)