Hypogammaglobulinemia in BLT humanized mice--an animal model of primary antibody deficiency.
Primary antibody deficiencies present clinically as reduced or absent plasma antibodies without another identified disorder that could explain the low immunoglobulin levels. Bone marrow-liver-thymus (BLT) humanized mice also exhibit primary antibody deficiency or hypogammaglobulinemia. Comprehensive...
Main Authors: | Francisco Martinez-Torres, Tomonori Nochi, Angela Wahl, J Victor Garcia, Paul W Denton |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2014-01-01
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Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC4182704?pdf=render |
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