Thalidomide ameliorates rosacea-like skin inflammation and suppresses NF-κB activation in keratinocytes

Thalidomide ameliorates rosacea-like skin inflammation and suppresses NF-κB activation in keratinocytes

Background: Rosacea is a chronic inflammatory skin disorder of uncertain etiology. Evidence suggests the underlying pathogenesis is modulated by abnormal inflammatory and vascular responses. Thalidomide is a synthetic derivative acid with anti-inflammatory and anti-angiogenic properties. However, it...

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Bibliographic Details
Main Authors: Mengting Chen, Hongfu Xie, Zhaohui Chen, San Xu, Ben Wang, Qinqin Peng, Ke Sha, Wenqin Xiao, Tangxiele Liu, Yiya Zhang, Ji Li, Zhili Deng
Format: Article
Language:English
Published: Elsevier 2019-08-01
Series:Biomedicine & Pharmacotherapy
Subjects:
Rosacea
LL37
Thalidomide
Inflammation
NF-κB
Angiogenesis
Online Access:http://www.sciencedirect.com/science/article/pii/S0753332219318955

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