BMI differences among in-hospital management and outcomes in patients with atrial fibrillation: findings from the Care for Cardiovascular Disease project in China
Abstract Background Underweight or obese status influences the prognosis of atrial fibrillation (AF). However, the association between stratification of body mass index (BMI) and in-hospital outcomes in patients with AF, remains lacking in China. Methods Using data from the Improving Care for Cardio...
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doaj-3cc6156dd97f42a9bda0fc5c1501fad72020-11-25T03:23:27ZengBMCBMC Cardiovascular Disorders1471-22612020-06-0120111210.1186/s12872-020-01544-8BMI differences among in-hospital management and outcomes in patients with atrial fibrillation: findings from the Care for Cardiovascular Disease project in ChinaFuxue Deng0Yan Zhang1Qiang Zhao2Yangyang Deng3Shanshan Gao4Lisha Zhang5Mengya Dong6Zuyi Yuan7Xinjun Lei8on behalf of the CCC-AF investigatorsDepartment of Cardiovascular Medicine, the Second Affiliated Hospital of Xi’an Jiaotong UniversityDepartment of Cardiovascular Medicine, the First Affiliated Hospital of Xi’an Jiaotong UniversityDepartment of Cardiovascular Medicine, the First Affiliated Hospital of Xi’an Jiaotong UniversityDepartment of Cardiovascular Medicine, the First Affiliated Hospital of Xi’an Jiaotong UniversityDepartment of Cardiovascular Medicine, the First Affiliated Hospital of Xi’an Jiaotong UniversityDepartment of Cardiovascular Medicine, the First Affiliated Hospital of Xi’an Jiaotong UniversityDepartment of Cardiovascular Medicine, the First Affiliated Hospital of Xi’an Jiaotong UniversityDepartment of Cardiovascular Medicine, the Second Affiliated Hospital of Xi’an Jiaotong UniversityDepartment of Cardiovascular Medicine, the Second Affiliated Hospital of Xi’an Jiaotong UniversityAbstract Background Underweight or obese status influences the prognosis of atrial fibrillation (AF). However, the association between stratification of body mass index (BMI) and in-hospital outcomes in patients with AF, remains lacking in China. Methods Using data from the Improving Care for Cardiovascular Disease in China-AF project, which was launched in February 2015 and recruited 150 hospitals in China, we compared characteristics, in-hospital treatments and clinical outcomes among the stratifications of BMI for Asians. Results A total of 15,867 AF patients with AF were enrolled, including 830 (5.23%) underweight, 4965 (31.29%) with normal weight, 3716 (23.42%) overweight, 5263 (33.17%) obese class I and 1093 (6.89%) obese class II participants. Compared with normal weight patients, underweight, overweight, and obese patients showed increased percentages of CHADS2 scores (3–6) and CHA2DS2-VASc scores (5–9). During hospitalization, overweight or obese patients showed greater use of rhythm control medications, anticoagulant drugs, and intervention therapies than underweight–normal weight patients. In adjusted logistic models, BMI was a strong predictor of in-hospital mortality. Especially, underweight BMI was associated with higher incidence of in-hospital mortality, with an adjusted odds ratio of 2.08 (95% confidence interval, 1.56–4.46; p = 0.04) than overweight and obese BMI. Conclusions Asian patients with AF and high BMI received more medical treatments and presented less adverse in-hospital outcomes compared with those with underweight–normal weight. Although low BMI may be associated with other comorbidities and advanced age, underweight BMI retained a negative correlation with all-cause mortality in the patients with AF during hospitalization.http://link.springer.com/article/10.1186/s12872-020-01544-8Atrial fibrillationBody mass indexMedical careClinical outcomes |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Fuxue Deng Yan Zhang Qiang Zhao Yangyang Deng Shanshan Gao Lisha Zhang Mengya Dong Zuyi Yuan Xinjun Lei on behalf of the CCC-AF investigators |
spellingShingle |
Fuxue Deng Yan Zhang Qiang Zhao Yangyang Deng Shanshan Gao Lisha Zhang Mengya Dong Zuyi Yuan Xinjun Lei on behalf of the CCC-AF investigators BMI differences among in-hospital management and outcomes in patients with atrial fibrillation: findings from the Care for Cardiovascular Disease project in China BMC Cardiovascular Disorders Atrial fibrillation Body mass index Medical care Clinical outcomes |
author_facet |
Fuxue Deng Yan Zhang Qiang Zhao Yangyang Deng Shanshan Gao Lisha Zhang Mengya Dong Zuyi Yuan Xinjun Lei on behalf of the CCC-AF investigators |
author_sort |
Fuxue Deng |
title |
BMI differences among in-hospital management and outcomes in patients with atrial fibrillation: findings from the Care for Cardiovascular Disease project in China |
title_short |
BMI differences among in-hospital management and outcomes in patients with atrial fibrillation: findings from the Care for Cardiovascular Disease project in China |
title_full |
BMI differences among in-hospital management and outcomes in patients with atrial fibrillation: findings from the Care for Cardiovascular Disease project in China |
title_fullStr |
BMI differences among in-hospital management and outcomes in patients with atrial fibrillation: findings from the Care for Cardiovascular Disease project in China |
title_full_unstemmed |
BMI differences among in-hospital management and outcomes in patients with atrial fibrillation: findings from the Care for Cardiovascular Disease project in China |
title_sort |
bmi differences among in-hospital management and outcomes in patients with atrial fibrillation: findings from the care for cardiovascular disease project in china |
publisher |
BMC |
series |
BMC Cardiovascular Disorders |
issn |
1471-2261 |
publishDate |
2020-06-01 |
description |
Abstract Background Underweight or obese status influences the prognosis of atrial fibrillation (AF). However, the association between stratification of body mass index (BMI) and in-hospital outcomes in patients with AF, remains lacking in China. Methods Using data from the Improving Care for Cardiovascular Disease in China-AF project, which was launched in February 2015 and recruited 150 hospitals in China, we compared characteristics, in-hospital treatments and clinical outcomes among the stratifications of BMI for Asians. Results A total of 15,867 AF patients with AF were enrolled, including 830 (5.23%) underweight, 4965 (31.29%) with normal weight, 3716 (23.42%) overweight, 5263 (33.17%) obese class I and 1093 (6.89%) obese class II participants. Compared with normal weight patients, underweight, overweight, and obese patients showed increased percentages of CHADS2 scores (3–6) and CHA2DS2-VASc scores (5–9). During hospitalization, overweight or obese patients showed greater use of rhythm control medications, anticoagulant drugs, and intervention therapies than underweight–normal weight patients. In adjusted logistic models, BMI was a strong predictor of in-hospital mortality. Especially, underweight BMI was associated with higher incidence of in-hospital mortality, with an adjusted odds ratio of 2.08 (95% confidence interval, 1.56–4.46; p = 0.04) than overweight and obese BMI. Conclusions Asian patients with AF and high BMI received more medical treatments and presented less adverse in-hospital outcomes compared with those with underweight–normal weight. Although low BMI may be associated with other comorbidities and advanced age, underweight BMI retained a negative correlation with all-cause mortality in the patients with AF during hospitalization. |
topic |
Atrial fibrillation Body mass index Medical care Clinical outcomes |
url |
http://link.springer.com/article/10.1186/s12872-020-01544-8 |
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