Prasugrel and Acquired Thrombotic Thrombocytopenic Purpura Associated with ADAMTS13 Activity Deficiency

We report a case of a 64-year-old male who, 44 days after starting treatment with prasugrel, presented with severe thrombocytopenia, anemia, renal failure, and severe ADAMTS13 activity deficiency, along with a high titer of autoantibodies to this protease.

Bibliographic Details
Main Authors: Yanet Parodis Lopez, Nery Sablon Gonzalez, Noel Lorenzo Villalba, Rafael Camacho Galvan, Jose Carlos Rodriguez Perez
Format: Article
Language:English
Published: SMC MEDIA SRL 2016-07-01
Series:European Journal of Case Reports in Internal Medicine
Subjects:
Online Access:http://ejcrim.com/index.php/EJCRIM/article/view/446
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spelling doaj-3cede46c40824835b37115b81145ced32020-11-25T01:09:01ZengSMC MEDIA SRLEuropean Journal of Case Reports in Internal Medicine2284-25942016-07-013510.12890/2016_000446163Prasugrel and Acquired Thrombotic Thrombocytopenic Purpura Associated with ADAMTS13 Activity DeficiencyYanet Parodis Lopez0Nery Sablon Gonzalez1Noel Lorenzo Villalba2Rafael Camacho Galvan3Jose Carlos Rodriguez Perez4Dr Negrin General University Hospital, Las Palmas de Gran Canaria, Las Palmas,Dr Negrin General University Hospital, Las Palmas de Gran Canaria, Las Palmas,Dr Negrin General University Hospital, Las Palmas de Gran Canaria, Las Palmas,Dr Negrin General University Hospital, Las Palmas de Gran Canaria, Las Palmas,Dr Negrin General University Hospital, Las Palmas de Gran Canaria, Las Palmas,We report a case of a 64-year-old male who, 44 days after starting treatment with prasugrel, presented with severe thrombocytopenia, anemia, renal failure, and severe ADAMTS13 activity deficiency, along with a high titer of autoantibodies to this protease.http://ejcrim.com/index.php/EJCRIM/article/view/446Thrombotic microangiopathythrombotic thrombocytopenic purpuraprasugrel
collection DOAJ
language English
format Article
sources DOAJ
author Yanet Parodis Lopez
Nery Sablon Gonzalez
Noel Lorenzo Villalba
Rafael Camacho Galvan
Jose Carlos Rodriguez Perez
spellingShingle Yanet Parodis Lopez
Nery Sablon Gonzalez
Noel Lorenzo Villalba
Rafael Camacho Galvan
Jose Carlos Rodriguez Perez
Prasugrel and Acquired Thrombotic Thrombocytopenic Purpura Associated with ADAMTS13 Activity Deficiency
European Journal of Case Reports in Internal Medicine
Thrombotic microangiopathy
thrombotic thrombocytopenic purpura
prasugrel
author_facet Yanet Parodis Lopez
Nery Sablon Gonzalez
Noel Lorenzo Villalba
Rafael Camacho Galvan
Jose Carlos Rodriguez Perez
author_sort Yanet Parodis Lopez
title Prasugrel and Acquired Thrombotic Thrombocytopenic Purpura Associated with ADAMTS13 Activity Deficiency
title_short Prasugrel and Acquired Thrombotic Thrombocytopenic Purpura Associated with ADAMTS13 Activity Deficiency
title_full Prasugrel and Acquired Thrombotic Thrombocytopenic Purpura Associated with ADAMTS13 Activity Deficiency
title_fullStr Prasugrel and Acquired Thrombotic Thrombocytopenic Purpura Associated with ADAMTS13 Activity Deficiency
title_full_unstemmed Prasugrel and Acquired Thrombotic Thrombocytopenic Purpura Associated with ADAMTS13 Activity Deficiency
title_sort prasugrel and acquired thrombotic thrombocytopenic purpura associated with adamts13 activity deficiency
publisher SMC MEDIA SRL
series European Journal of Case Reports in Internal Medicine
issn 2284-2594
publishDate 2016-07-01
description We report a case of a 64-year-old male who, 44 days after starting treatment with prasugrel, presented with severe thrombocytopenia, anemia, renal failure, and severe ADAMTS13 activity deficiency, along with a high titer of autoantibodies to this protease.
topic Thrombotic microangiopathy
thrombotic thrombocytopenic purpura
prasugrel
url http://ejcrim.com/index.php/EJCRIM/article/view/446
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