β-Cyclodextrin/Isopentyl Caffeate Inclusion Complex: Synthesis, Characterization and Antileishmanial Activity

β-Cyclodextrin/Isopentyl Caffeate Inclusion Complex: Synthesis, Characterization and Antileishmanial Activity

Isopentyl caffeate (ICaf) is a bioactive ester widely distributed in nature. Our patented work has shown promising results of this molecule against Leishmania. However, ICaf shows poor solubility, which limits its usage in clinical settings. In this work, we have proposed the development of an inclu...

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Bibliographic Details
Main Authors: Carine S. F. Marques, Nathalia S. Barreto, Simone S. C. de Oliveira, André L. S. Santos, Marta H. Branquinha, Damião P. de Sousa, Mayara Castro, Luciana N. Andrade, Matheus M. Pereira, Classius F. da Silva, Marco V. Chaud, Sona Jain, Alini T. Fricks, Eliana B. Souto, Patricia Severino
Format: Article
Language:English
Published: MDPI AG 2020-09-01
Series:Molecules
Subjects:
isopentyl caffeate
β-cyclodextrin
inclusion complex
leishmania
Online Access:https://www.mdpi.com/1420-3049/25/18/4181

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