Wnt signalling pathway parameters for mammalian cells.

Wnt/β-catenin signalling regulates cell fate, survival, proliferation and differentiation at many stages of mammalian development and pathology. Mutations of two key proteins in the pathway, APC and β-catenin, have been implicated in a range of cancers, including colorectal cancer. Activation of Wnt...

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Bibliographic Details
Main Authors: Chin Wee Tan, Bruce S Gardiner, Yumiko Hirokawa, Meredith J Layton, David W Smith, Antony W Burgess
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3283727?pdf=render

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