Wnt signalling pathway parameters for mammalian cells.
Wnt/β-catenin signalling regulates cell fate, survival, proliferation and differentiation at many stages of mammalian development and pathology. Mutations of two key proteins in the pathway, APC and β-catenin, have been implicated in a range of cancers, including colorectal cancer. Activation of Wnt...
Main Authors: | Chin Wee Tan, Bruce S Gardiner, Yumiko Hirokawa, Meredith J Layton, David W Smith, Antony W Burgess |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2012-01-01
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Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC3283727?pdf=render |
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