Plasma Glucose and Serum Ceruloplasmin in Metabolic Syndrome and Diabetes Mellitus Type 2

• Main Authors: Ashok Kumar Jeppu, Asha Augusthy, Kavitha Ashok Kumar
• Format: Article
• Language: English
• Published: HATASO 2016-04-01
• Series: Recent Advances in Biology and Medicine
• Subjects: Diabetes mellitus; Metabolic syndrome; Ceruloplasmin; Glucose
• Online Access: https://rabm.scholasticahq.com/article/651-plasma-glucose-and-serum-ceruloplasmin-in-metabolic-syndrome-and-diabetes-mellitus-type-2

Diabetes mellitus type 2 and metabolic syndrome are conditions associated with insulin resistance and hyperglycemia. Metabolic syndrome is a risk factor for diabetes mellitus type 2. Plasma glucose (fasting/postprandial) and serum ceruloplasmin levels and their relationship were studied. Study population consisted of 150 individuals—50 individuals with diabetes mellitus type 2, 50 individuals with metabolic syndrome, and 50 age- and sex-matched healthy controls. Plasma levels of fasting and postprandial glucose were measured along with serum ceruloplasmin. Data was analyzed by ANOVA and Pearson correlation. The fasting and postprandial plasma glucose levels in metabolic syndrome and diabetes mellitus type 2 were increased when compared to control. Serum ceruloplasmin level was 327.8 ± 68.9 in control, 227.3 ± 46.8 in metabolic syndrome, and 194.0 ± 49.6 in diabetes mellitus type 2 individuals. There was a statistically significant negative correlation between the fasting, postprandial plasma glucose, and serum ceruloplasmin in type 2 diabetes mellitus.