Dysphagia and disrupted cranial nerve development in a mouse model of DiGeorge (22q11) deletion syndrome

Dysphagia and disrupted cranial nerve development in a mouse model of DiGeorge (22q11) deletion syndrome

We assessed feeding-related developmental anomalies in the LgDel mouse model of chromosome 22q11 deletion syndrome (22q11DS), a common developmental disorder that frequently includes perinatal dysphagia – debilitating feeding, swallowing and nutrition difficulties from birth onward – within its phen...

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Bibliographic Details
Main Authors: Beverly A. Karpinski, Thomas M. Maynard, Matthew S. Fralish, Samer Nuwayhid, Irene E. Zohn, Sally A. Moody, Anthony-S. LaMantia
Format: Article
Language:English
Published: The Company of Biologists 2014-02-01
Series:Disease Models & Mechanisms
Subjects:
DiGeorge
22q11 deletion syndrome
Cranial nerve development
Dysphagia
Hindbrain patterning
Online Access:http://dmm.biologists.org/content/7/2/245

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