Adult hippocampal neurogenesis and pattern separation in DG: A role for feedback inhibition in modulating sparseness to govern population-based coding
The dentate gyrus (DG) of mammals harbors neural stem cells that generate new dentate granule cells (DGCs) throughout life. Behavioral studies using the contextual fear discrimination paradigm have found that selectively augmenting or blocking adult hippocampal neurogenesis enhances or impairs disc...
Main Authors: | Kathleen eMcAvoy, Antoine eBesnard, Amar eSahay |
---|---|
Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2015-08-01
|
Series: | Frontiers in Systems Neuroscience |
Subjects: | |
Online Access: | http://journal.frontiersin.org/Journal/10.3389/fnsys.2015.00120/full |
Similar Items
-
Adult Hippocampal Neurogenesis: Regulation and Possible Functional and Clinical Correlates
by: Pedro Baptista, et al.
Published: (2018-06-01) -
Reconsidering hippocampal neurogenesis in Alzheimer’s disease
by: Alonso eMartinez-Canabal, et al.
Published: (2014-06-01) -
The Role of Adult Hippocampal Neurogenesis in Learning and Memory Function
by: Zülal Kaptan, et al.
Published: (2016-12-01) -
Neurogenesis paradoxically decreases both pattern separation and memory interference
by: Rory eFinnegan, et al.
Published: (2015-10-01) -
Adult neurogenesis modifies excitability of the dentate gyrus
by: Taruna eIkrar, et al.
Published: (2013-12-01)