Adult hippocampal neurogenesis and pattern separation in DG: A role for feedback inhibition in modulating sparseness to govern population-based coding

The dentate gyrus (DG) of mammals harbors neural stem cells that generate new dentate granule cells (DGCs) throughout life. Behavioral studies using the contextual fear discrimination paradigm have found that selectively augmenting or blocking adult hippocampal neurogenesis enhances or impairs disc...

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Bibliographic Details
Main Authors: Kathleen eMcAvoy, Antoine eBesnard, Amar eSahay
Format: Article
Published: Frontiers Media S.A. 2015-08-01
Series:Frontiers in Systems Neuroscience
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