Toward a Biological, Psychological and Familial Approach of Eating Disorders at Onset: Case-Control ANOBAS Study
Eating disorders (ED) are considered as heterogeneous disorders with a complex multifactor etiology that involves biological and environmental interaction.Objective: The aim was to identify specific ED bio-psychological-familial correlates at illness onset.Methods: A case-control (1:1) design was ap...
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doaj-3d200a6a1e8c4d348ca3dd71825ce5632021-09-09T09:04:31ZengFrontiers Media S.A.Frontiers in Psychology1664-10782021-09-011210.3389/fpsyg.2021.714414714414Toward a Biological, Psychological and Familial Approach of Eating Disorders at Onset: Case-Control ANOBAS StudyAna Rosa Sepúlveda0Alba Moreno-Encinas1José Angel Martínez-Huertas2Dimitra Anastasiadou3Esther Nova4Ascensión Marcos5Sonia Gómez-Martínez6José Ramón Villa-Asensi7Encarna Mollejo8Montserrat Graell9Montserrat Graell10Department of Biological and Health Psychology, School of Psychology, Autonomous University of Madrid, Madrid, SpainDepartment of Biological and Health Psychology, School of Psychology, Autonomous University of Madrid, Madrid, SpainDepartment of Cognitive Psychology, School of Psychology, Autonomous University of Madrid, Madrid, SpainDepartment of Biological and Health Psychology, School of Psychology, Autonomous University of Madrid, Madrid, SpainImmunonutrition Research Group, Department of Metabolism and Nutrition, Institute of Food Science, Technology and Nutrition (ICTAN), Spanish National Research Council (CSIC), Madrid, SpainImmunonutrition Research Group, Department of Metabolism and Nutrition, Institute of Food Science, Technology and Nutrition (ICTAN), Spanish National Research Council (CSIC), Madrid, SpainImmunonutrition Research Group, Department of Metabolism and Nutrition, Institute of Food Science, Technology and Nutrition (ICTAN), Spanish National Research Council (CSIC), Madrid, SpainPediatric Pneumology, Niño Jesús University Children’s Hospital, Madrid, SpainPsychiatry Service, Hospital Universitario del Sureste, Arganda del Rey, SpainDepartment of Child and Adolescent Psychiatry and Psychology, Niño Jesús University Children’s Hospital, Madrid, SpainCIBERSAM, Madrid, SpainEating disorders (ED) are considered as heterogeneous disorders with a complex multifactor etiology that involves biological and environmental interaction.Objective: The aim was to identify specific ED bio-psychological-familial correlates at illness onset.Methods: A case-control (1:1) design was applied, which studied 50 adolescents diagnosed with ED at onset (12–17 years old) and their families, paired by age and parents’ socio-educational level with three control samples (40 with an affective disorder, 40 with asthma, and 50 with no pathology) and their respective families. Biological, psychological, and familial correlates were assessed using interviews, standardized questionnaires, and a blood test.Results: After performing conditional logistic regression models for each type of variable, those correlates that showed to be specific for ED were included in a global exploratory model (R2 = 0.44). The specific correlates identified associated to the onset of an ED were triiodothyronine (T3) as the main specific biological correlate; patients’ drive for thinness, perfectionism and anxiety as the main psychological correlates; and fathers’ emotional over-involvement and depression, and mothers’ anxiety as the main familial correlates.Conclusion: To our knowledge, this is the first study to use three specific control groups assessed through standardized interviews, and to collect a wide variety of data at the illness onset. This study design has allowed to explore which correlates, among those measured, were specific to EDs; finding that perfectionism and family emotional over-involvement, as well as the T3 hormone were relevant to discern ED cases at the illness onset from other adolescents with or without a concurrent pathology.https://www.frontiersin.org/articles/10.3389/fpsyg.2021.714414/fulleating disorderscase-control studybiological correlatespsychological correlatesfamilial correlates |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Ana Rosa Sepúlveda Alba Moreno-Encinas José Angel Martínez-Huertas Dimitra Anastasiadou Esther Nova Ascensión Marcos Sonia Gómez-Martínez José Ramón Villa-Asensi Encarna Mollejo Montserrat Graell Montserrat Graell |
spellingShingle |
Ana Rosa Sepúlveda Alba Moreno-Encinas José Angel Martínez-Huertas Dimitra Anastasiadou Esther Nova Ascensión Marcos Sonia Gómez-Martínez José Ramón Villa-Asensi Encarna Mollejo Montserrat Graell Montserrat Graell Toward a Biological, Psychological and Familial Approach of Eating Disorders at Onset: Case-Control ANOBAS Study Frontiers in Psychology eating disorders case-control study biological correlates psychological correlates familial correlates |
author_facet |
Ana Rosa Sepúlveda Alba Moreno-Encinas José Angel Martínez-Huertas Dimitra Anastasiadou Esther Nova Ascensión Marcos Sonia Gómez-Martínez José Ramón Villa-Asensi Encarna Mollejo Montserrat Graell Montserrat Graell |
author_sort |
Ana Rosa Sepúlveda |
title |
Toward a Biological, Psychological and Familial Approach of Eating Disorders at Onset: Case-Control ANOBAS Study |
title_short |
Toward a Biological, Psychological and Familial Approach of Eating Disorders at Onset: Case-Control ANOBAS Study |
title_full |
Toward a Biological, Psychological and Familial Approach of Eating Disorders at Onset: Case-Control ANOBAS Study |
title_fullStr |
Toward a Biological, Psychological and Familial Approach of Eating Disorders at Onset: Case-Control ANOBAS Study |
title_full_unstemmed |
Toward a Biological, Psychological and Familial Approach of Eating Disorders at Onset: Case-Control ANOBAS Study |
title_sort |
toward a biological, psychological and familial approach of eating disorders at onset: case-control anobas study |
publisher |
Frontiers Media S.A. |
series |
Frontiers in Psychology |
issn |
1664-1078 |
publishDate |
2021-09-01 |
description |
Eating disorders (ED) are considered as heterogeneous disorders with a complex multifactor etiology that involves biological and environmental interaction.Objective: The aim was to identify specific ED bio-psychological-familial correlates at illness onset.Methods: A case-control (1:1) design was applied, which studied 50 adolescents diagnosed with ED at onset (12–17 years old) and their families, paired by age and parents’ socio-educational level with three control samples (40 with an affective disorder, 40 with asthma, and 50 with no pathology) and their respective families. Biological, psychological, and familial correlates were assessed using interviews, standardized questionnaires, and a blood test.Results: After performing conditional logistic regression models for each type of variable, those correlates that showed to be specific for ED were included in a global exploratory model (R2 = 0.44). The specific correlates identified associated to the onset of an ED were triiodothyronine (T3) as the main specific biological correlate; patients’ drive for thinness, perfectionism and anxiety as the main psychological correlates; and fathers’ emotional over-involvement and depression, and mothers’ anxiety as the main familial correlates.Conclusion: To our knowledge, this is the first study to use three specific control groups assessed through standardized interviews, and to collect a wide variety of data at the illness onset. This study design has allowed to explore which correlates, among those measured, were specific to EDs; finding that perfectionism and family emotional over-involvement, as well as the T3 hormone were relevant to discern ED cases at the illness onset from other adolescents with or without a concurrent pathology. |
topic |
eating disorders case-control study biological correlates psychological correlates familial correlates |
url |
https://www.frontiersin.org/articles/10.3389/fpsyg.2021.714414/full |
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