Inhibition of IL-13 and IL-13Rα2 Expression by IL-32θ in Human Monocytic Cells Requires PKCδ and STAT3 Association

Inhibition of IL-13 and IL-13Rα2 Expression by IL-32θ in Human Monocytic Cells Requires PKCδ and STAT3 Association

Interleukin (IL)-32θ, a newly identified IL-32 isoform, has been reported to exert pro-inflammatory effects through the association with protein kinase C delta (PKCδ). In this study, we further examined the effects of IL-32θ on IL-13 and IL-13Rα2 expression and th...

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Bibliographic Details
Main Authors: Thu-Huyen Pham, Yesol Bak, Jae-Wook Oh, Jingi Hong, Seungyeoun Lee, Jin Tae Hong, Do-Young Yoon
Format: Article
Language:English
Published: MDPI AG 2019-04-01
Series:International Journal of Molecular Sciences
Subjects:
IL-13Rα2
IL-13 signaling
IL-32θ
STAT3 activation
PKCδ
Online Access:https://www.mdpi.com/1422-0067/20/8/1949

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