Association between Polymorphisms of <i>OCT1</i> and Metabolic Response to Metformin in Women with Polycystic Ovary Syndrome

Association between Polymorphisms of <i>OCT1</i> and Metabolic Response to Metformin in Women with Polycystic Ovary Syndrome

Insulin-sensitizer treatment with metformin is widely used in polycystic ovary syndrome (PCOS). However, the treatment effectiveness shows individual differences in PCOS patients. Organic cation transporter (OCT) 1 and 2 have been reported to mediate metformin transport in the liver and kidney, resp...

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Bibliographic Details
Main Authors: Hui Hua Chang, Yuan-Shuo Hsueh, Yung Wen Cheng, Huang-Tz Ou, Meng-Hsing Wu
Format: Article
Language:English
Published: MDPI AG 2019-04-01
Series:International Journal of Molecular Sciences
Subjects:
polycystic ovary syndrome
metformin
polymorphisms
OCT1
Online Access:https://www.mdpi.com/1422-0067/20/7/1720

Internet

https://www.mdpi.com/1422-0067/20/7/1720

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