Metabolomics data of Mitragyna speciosa leaf using LC-ESI-TOF-MS
Mitragyna speciosa is a psychoactive plant known as “ketum” in Malaysia and “kratom” in Thailand. This plant is distinctly known to produce two important alkaloids, namely mitragynine (MG) and 7-hydroxymitragynine (7-OH-MG) that can bind to opioid receptors [1]. MG was reported to exhibit antidepres...
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doaj-3d4641c1cb57413a8e0be3fa17cb7ca02020-11-25T01:31:37ZengElsevierData in Brief2352-34092018-06-011812121216Metabolomics data of Mitragyna speciosa leaf using LC-ESI-TOF-MSRubashiny Veeramohan0Kamalrul Azlan Azizan1Wan Mohd Aizat2Hoe-Han Goh3Sharif Mahsufi Mansor4Nur Sabrina Mohd Yusof5Syarul Nataqain Baharum6Chyan Leong Ng7Institute of Systems Biology (INBIOSIS), Universiti Kebangsaan Malaysia (UKM), 43600 Bangi, Selangor, MalaysiaInstitute of Systems Biology (INBIOSIS), Universiti Kebangsaan Malaysia (UKM), 43600 Bangi, Selangor, MalaysiaInstitute of Systems Biology (INBIOSIS), Universiti Kebangsaan Malaysia (UKM), 43600 Bangi, Selangor, MalaysiaInstitute of Systems Biology (INBIOSIS), Universiti Kebangsaan Malaysia (UKM), 43600 Bangi, Selangor, MalaysiaCentre for Drug Research, Universiti Sains Malaysia, 11800 Minden, Penang, MalaysiaCentre for Drug Research, Universiti Sains Malaysia, 11800 Minden, Penang, MalaysiaInstitute of Systems Biology (INBIOSIS), Universiti Kebangsaan Malaysia (UKM), 43600 Bangi, Selangor, MalaysiaInstitute of Systems Biology (INBIOSIS), Universiti Kebangsaan Malaysia (UKM), 43600 Bangi, Selangor, Malaysia; Corresponding author.Mitragyna speciosa is a psychoactive plant known as “ketum” in Malaysia and “kratom” in Thailand. This plant is distinctly known to produce two important alkaloids, namely mitragynine (MG) and 7-hydroxymitragynine (7-OH-MG) that can bind to opioid receptors [1]. MG was reported to exhibit antidepressant properties in animal studies [2]. These compounds were also proposed to have the potential to replace opioid analgesics with much lower risks of side effects [3]. To date, there are only over 40 metabolites identified in M. speciosa [4,5]. To obtain a more complete profile of secondary metabolites in ketum, we performed metabolomics study using mature leaves of the green M. speciosa variety. The leaf samples were extracted using methanol prior to liquid chromatography-electrospray ionization-time of flight-mass spectrometry (LC-ESI-TOF-MS) analysis. This data can be useful to for the identification of unknown metabolites that are associated with alkaloid biosynthesis pathway in M. speciosa. Keywords: Alkaloids, LC–MS, Metabolomics, Methanolic extraction, Mitragyna speciosahttp://www.sciencedirect.com/science/article/pii/S2352340918303524 |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Rubashiny Veeramohan Kamalrul Azlan Azizan Wan Mohd Aizat Hoe-Han Goh Sharif Mahsufi Mansor Nur Sabrina Mohd Yusof Syarul Nataqain Baharum Chyan Leong Ng |
spellingShingle |
Rubashiny Veeramohan Kamalrul Azlan Azizan Wan Mohd Aizat Hoe-Han Goh Sharif Mahsufi Mansor Nur Sabrina Mohd Yusof Syarul Nataqain Baharum Chyan Leong Ng Metabolomics data of Mitragyna speciosa leaf using LC-ESI-TOF-MS Data in Brief |
author_facet |
Rubashiny Veeramohan Kamalrul Azlan Azizan Wan Mohd Aizat Hoe-Han Goh Sharif Mahsufi Mansor Nur Sabrina Mohd Yusof Syarul Nataqain Baharum Chyan Leong Ng |
author_sort |
Rubashiny Veeramohan |
title |
Metabolomics data of Mitragyna speciosa leaf using LC-ESI-TOF-MS |
title_short |
Metabolomics data of Mitragyna speciosa leaf using LC-ESI-TOF-MS |
title_full |
Metabolomics data of Mitragyna speciosa leaf using LC-ESI-TOF-MS |
title_fullStr |
Metabolomics data of Mitragyna speciosa leaf using LC-ESI-TOF-MS |
title_full_unstemmed |
Metabolomics data of Mitragyna speciosa leaf using LC-ESI-TOF-MS |
title_sort |
metabolomics data of mitragyna speciosa leaf using lc-esi-tof-ms |
publisher |
Elsevier |
series |
Data in Brief |
issn |
2352-3409 |
publishDate |
2018-06-01 |
description |
Mitragyna speciosa is a psychoactive plant known as “ketum” in Malaysia and “kratom” in Thailand. This plant is distinctly known to produce two important alkaloids, namely mitragynine (MG) and 7-hydroxymitragynine (7-OH-MG) that can bind to opioid receptors [1]. MG was reported to exhibit antidepressant properties in animal studies [2]. These compounds were also proposed to have the potential to replace opioid analgesics with much lower risks of side effects [3]. To date, there are only over 40 metabolites identified in M. speciosa [4,5]. To obtain a more complete profile of secondary metabolites in ketum, we performed metabolomics study using mature leaves of the green M. speciosa variety. The leaf samples were extracted using methanol prior to liquid chromatography-electrospray ionization-time of flight-mass spectrometry (LC-ESI-TOF-MS) analysis. This data can be useful to for the identification of unknown metabolites that are associated with alkaloid biosynthesis pathway in M. speciosa. Keywords: Alkaloids, LC–MS, Metabolomics, Methanolic extraction, Mitragyna speciosa |
url |
http://www.sciencedirect.com/science/article/pii/S2352340918303524 |
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