Substrate Stiffness Regulates Cholesterol Efflux in Smooth Muscle Cells
The infiltration and deposition of cholesterol in the arterial wall play an important role in the initiation and development of atherosclerosis. Smooth muscle cells (SMCs) are the major cell type in the intima. Upon exposure to cholesterol, SMCs may undergo a phenotype switching into foam cells. Mea...
Main Authors: | Xiuli Mao, Yiling Tan, Huali Wang, Song Li, Yue Zhou |
---|---|
Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2021-05-01
|
Series: | Frontiers in Cell and Developmental Biology |
Subjects: | |
Online Access: | https://www.frontiersin.org/articles/10.3389/fcell.2021.648715/full |
Similar Items
-
Sesamin Enhances Cholesterol Efflux in RAW264.7 Macrophages
by: Nan Liu, et al.
Published: (2014-06-01) -
Cholesterol delivered to macrophages by oxidized low density lipoprotein is sequestered in lysosomes and fails to efflux normally
by: Baljinder S. Dhaliwal, et al.
Published: (2000-10-01) -
Sterol synthesis is up-regulated in cholesterol-loaded pigeon macrophages during induction of cholesterol efflux
by: Brian K. Nordskog, et al.
Published: (1999-10-01) -
Cholesterol Efflux: Does It Contribute to Aortic Stiffening?
by: Shutan Liao, et al.
Published: (2018-05-01) -
Regulation of Lipid Droplet Cholesterol Efflux from Macrophage Foam Cells: a Role for Oxysterols and Autophagy
by: Ouimet, Mireille
Published: (2011)