Patient Derived Xenografts Expand Human Primary Pancreatic Tumor Tissue Availability for ex vivo Irreversible Electroporation Testing

New methods of tumor ablation have shown exciting efficacy in pre-clinical models but often demonstrate limited success in the clinic. Due to a lack of quality or quantity in primary malignant tissue specimens, therapeutic development and optimization studies are typically conducted on healthy tissu...

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Bibliographic Details
Main Authors: Rebecca M. Brock, Natalie Beitel-White, Sheryl Coutermarsh-Ott, Douglas J. Grider, Melvin F. Lorenzo, Veronica M. Ringel-Scaia, Navid Manuchehrabadi, Robert C. G. Martin, Rafael V. Davalos, Irving C. Allen
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-05-01
Series:Frontiers in Oncology
Subjects:
PDX
Online Access:https://www.frontiersin.org/article/10.3389/fonc.2020.00843/full

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