Club cell-specific role of programmed cell death 5 in pulmonary fibrosis

Idiopathic pulmonary fibrosis (IPF) is a fatal adult lung disease. Here the authors investigate the functional significance of PDCD5 in club cells as a mediator of lung fibrosis and potential therapeutic target for IPF.

Bibliographic Details
Main Authors:	Soo-Yeon Park, Jung Yeon Hong, Soo Yeon Lee, Seung-Hyun Lee, Mi Jeong Kim, Soo Yeon Kim, Kyung Won Kim, Hyo Sup Shim, Moo Suk Park, Chun Geun Lee, Jack A. Elias, Myung Hyun Sohn, Ho-Geun Yoon
Format:	Article
Language:	English
Published:	Nature Publishing Group 2021-05-01
Series:	Nature Communications
Online Access:	https://doi.org/10.1038/s41467-021-23277-8

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spelling	doaj-3d4d03ec3ef149fe84412d2547f541c92021-05-23T11:11:59ZengNature Publishing GroupNature Communications2041-17232021-05-0112111310.1038/s41467-021-23277-8Club cell-specific role of programmed cell death 5 in pulmonary fibrosisSoo-Yeon Park0Jung Yeon Hong1Soo Yeon Lee2Seung-Hyun Lee3Mi Jeong Kim4Soo Yeon Kim5Kyung Won Kim6Hyo Sup Shim7Moo Suk Park8Chun Geun Lee9Jack A. Elias10Myung Hyun Sohn11Ho-Geun Yoon12Department of Biochemistry and Molecular Biology, Severance Medical Research Institute, Brain Korea 21 PLUS Project for Medical Sciences, Yonsei University College of MedicineDepartment of Pediatrics and Institute of Allergy, Severance Medical Research Institute, Brain Korea 21 PLUS Project for Medical Sciences, Yonsei University College of MedicineDepartment of Biochemistry and Molecular Biology, Severance Medical Research Institute, Brain Korea 21 PLUS Project for Medical Sciences, Yonsei University College of MedicineDepartment of Biochemistry and Molecular Biology, Severance Medical Research Institute, Brain Korea 21 PLUS Project for Medical Sciences, Yonsei University College of MedicineDepartment of Biochemistry and Molecular Biology, Severance Medical Research Institute, Brain Korea 21 PLUS Project for Medical Sciences, Yonsei University College of MedicineDepartment of Pediatrics and Institute of Allergy, Severance Medical Research Institute, Brain Korea 21 PLUS Project for Medical Sciences, Yonsei University College of MedicineDepartment of Pediatrics and Institute of Allergy, Severance Medical Research Institute, Brain Korea 21 PLUS Project for Medical Sciences, Yonsei University College of MedicineDepartment of Pathology, Yonsei University College of MedicineDivision of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Yonsei University College of MedicineMolecular Microbiology and Immunology, Brown UniversityMolecular Microbiology and Immunology, Brown UniversityDepartment of Pediatrics and Institute of Allergy, Severance Medical Research Institute, Brain Korea 21 PLUS Project for Medical Sciences, Yonsei University College of MedicineDepartment of Biochemistry and Molecular Biology, Severance Medical Research Institute, Brain Korea 21 PLUS Project for Medical Sciences, Yonsei University College of MedicineIdiopathic pulmonary fibrosis (IPF) is a fatal adult lung disease. Here the authors investigate the functional significance of PDCD5 in club cells as a mediator of lung fibrosis and potential therapeutic target for IPF.https://doi.org/10.1038/s41467-021-23277-8
collection	DOAJ
language	English
format	Article
sources	DOAJ
author	Soo-Yeon Park Jung Yeon Hong Soo Yeon Lee Seung-Hyun Lee Mi Jeong Kim Soo Yeon Kim Kyung Won Kim Hyo Sup Shim Moo Suk Park Chun Geun Lee Jack A. Elias Myung Hyun Sohn Ho-Geun Yoon
spellingShingle	Soo-Yeon Park Jung Yeon Hong Soo Yeon Lee Seung-Hyun Lee Mi Jeong Kim Soo Yeon Kim Kyung Won Kim Hyo Sup Shim Moo Suk Park Chun Geun Lee Jack A. Elias Myung Hyun Sohn Ho-Geun Yoon Club cell-specific role of programmed cell death 5 in pulmonary fibrosis Nature Communications
author_facet	Soo-Yeon Park Jung Yeon Hong Soo Yeon Lee Seung-Hyun Lee Mi Jeong Kim Soo Yeon Kim Kyung Won Kim Hyo Sup Shim Moo Suk Park Chun Geun Lee Jack A. Elias Myung Hyun Sohn Ho-Geun Yoon
author_sort	Soo-Yeon Park
title	Club cell-specific role of programmed cell death 5 in pulmonary fibrosis
title_short	Club cell-specific role of programmed cell death 5 in pulmonary fibrosis
title_full	Club cell-specific role of programmed cell death 5 in pulmonary fibrosis
title_fullStr	Club cell-specific role of programmed cell death 5 in pulmonary fibrosis
title_full_unstemmed	Club cell-specific role of programmed cell death 5 in pulmonary fibrosis
title_sort	club cell-specific role of programmed cell death 5 in pulmonary fibrosis
publisher	Nature Publishing Group
series	Nature Communications
issn	2041-1723
publishDate	2021-05-01
description	Idiopathic pulmonary fibrosis (IPF) is a fatal adult lung disease. Here the authors investigate the functional significance of PDCD5 in club cells as a mediator of lung fibrosis and potential therapeutic target for IPF.
url	https://doi.org/10.1038/s41467-021-23277-8
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Club cell-specific role of programmed cell death 5 in pulmonary fibrosis

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