EVALUATION OF EPIDEMIOLOGIC EFFECTIVENESS OF INFLUENZA INACTIVATED POLYMER-SUBUNIT VACCINE IN SCHOOLCHILDREN

• Main Author: T.N. Il'ina
• Format: Article
• Language: English
• Published: "Paediatrician" Publishers LLC 2009-01-01
• Series: Voprosy Sovremennoj Pediatrii
• Online Access: http://vsp.spr-journal.ru:80/jour/article/view/1168

<em>Present study was dedicated to the assessment of the «Grippol plus» polymer-subunit vaccine effectiveness in Moscow region’ Podolsk town schoolchildren in season 2008–2009. The study included 3203 participants (1950 vaccineers and 1253 non-vaccineers). Post-vaccination influenza and acute respiratory infections (ARIs) morbidity 6-months monitoring demonstrated high Grippol effectiveness. It was shown that vaccineers’ influenza morbidity rate was 4,7-times lower than in non-vaccinated schoolchildren. Immunized children’ ARIs morbidity was 1,4 times lower in comparison with other. Grippol effectiveness indexes were 4,7 и 78,7%. An important role for herd immunity protection was also demonstrated clearly by means of overall influenza and ARIs morbidity level decline. The schools with high vaccination coverage ( 60% of children) showed the overall morbidity rate 40% lower than that in schools with low immunization coverage.</em><br /><strong><em>Key words: schoolchildren, influenza, ARI, vaccination, collective immunity.</em></strong><br /><span style="text-decoration: underline;"><em>(<em><em><em>Voprosy sovremennoi pediatrii — </em></em></em>Current Pediatrics. 2009;8(5):<em>47-51</em>)</em></span>