Life-threatening autoimmune hemolytic anemia and idiopathic thrombocytopenic purpura: successful seletive splenic artery embolization
Selective splenic artery embolization (SSAE) is a nonsurgical intervention characterized by the transcatheter occlusion of the splenic artery and/or its branch vessels using metallic coils or other embolic devices. It has been applied for the management of splenic trauma, hypersplenism with portal h...
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doaj-3d62d6b799ba4b0f9d95f9e569d5ec212020-11-25T00:49:53ZengPAGEPress PublicationsMediterranean Journal of Hematology and Infectious Diseases2035-30062016-04-0180e2016020e201602010.4084/mjhid.2016.0201609Life-threatening autoimmune hemolytic anemia and idiopathic thrombocytopenic purpura: successful seletive splenic artery embolizationmatteo molicaFulvio MassaroGiorgia AnnechiniErminia BaldacciGianna maria D'eliaRiccardo RosatiSilvia maria trisoliniPaola VolpicelliRobin FoàSaveria CapriaSelective splenic artery embolization (SSAE) is a nonsurgical intervention characterized by the transcatheter occlusion of the splenic artery and/or its branch vessels using metallic coils or other embolic devices. It has been applied for the management of splenic trauma, hypersplenism with portal hypertension, hereditary spherocytosis, thalassemia and splenic hemangioma. We hereby describe a case of a patient affected by idiopathic thrombocytopenic purpura (ITP) and warm auto-immune hemolytic anemia (AIHA) both resistant to immunosuppressive and biological therapies, not eligible for a surgical intervention because of her critical conditions. She underwent SSAE and achieved a hematologic complete response within a few days without complications. SSAE is a minimally invasive procedure to date not considered a standard option in the management of AIHA and ITP. However, following the progressive improvement of the techniques, its indications have been extended, with a reduction in morbidity and mortality compared to splenectomy in patients with critical clinical conditions. SSAE was a lifesaving therapeutic approach for our patient and it may represent a real alternative for the treatment of resistant AIHA and ITP patients not eligible for splenectomy.http://www.mjhid.org/index.php/mjhid/article/view/2544Selective splenic artery embolization, warm auto-immune hemolytic anemia,idiopathic thrombocytopenic purpura |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
matteo molica Fulvio Massaro Giorgia Annechini Erminia Baldacci Gianna maria D'elia Riccardo Rosati Silvia maria trisolini Paola Volpicelli Robin Foà Saveria Capria |
spellingShingle |
matteo molica Fulvio Massaro Giorgia Annechini Erminia Baldacci Gianna maria D'elia Riccardo Rosati Silvia maria trisolini Paola Volpicelli Robin Foà Saveria Capria Life-threatening autoimmune hemolytic anemia and idiopathic thrombocytopenic purpura: successful seletive splenic artery embolization Mediterranean Journal of Hematology and Infectious Diseases Selective splenic artery embolization, warm auto-immune hemolytic anemia,idiopathic thrombocytopenic purpura |
author_facet |
matteo molica Fulvio Massaro Giorgia Annechini Erminia Baldacci Gianna maria D'elia Riccardo Rosati Silvia maria trisolini Paola Volpicelli Robin Foà Saveria Capria |
author_sort |
matteo molica |
title |
Life-threatening autoimmune hemolytic anemia and idiopathic thrombocytopenic purpura: successful seletive splenic artery embolization |
title_short |
Life-threatening autoimmune hemolytic anemia and idiopathic thrombocytopenic purpura: successful seletive splenic artery embolization |
title_full |
Life-threatening autoimmune hemolytic anemia and idiopathic thrombocytopenic purpura: successful seletive splenic artery embolization |
title_fullStr |
Life-threatening autoimmune hemolytic anemia and idiopathic thrombocytopenic purpura: successful seletive splenic artery embolization |
title_full_unstemmed |
Life-threatening autoimmune hemolytic anemia and idiopathic thrombocytopenic purpura: successful seletive splenic artery embolization |
title_sort |
life-threatening autoimmune hemolytic anemia and idiopathic thrombocytopenic purpura: successful seletive splenic artery embolization |
publisher |
PAGEPress Publications |
series |
Mediterranean Journal of Hematology and Infectious Diseases |
issn |
2035-3006 |
publishDate |
2016-04-01 |
description |
Selective splenic artery embolization (SSAE) is a nonsurgical intervention characterized by the transcatheter occlusion of the splenic artery and/or its branch vessels using metallic coils or other embolic devices. It has been applied for the management of splenic trauma, hypersplenism with portal hypertension, hereditary spherocytosis, thalassemia and splenic hemangioma. We hereby describe a case of a patient affected by idiopathic thrombocytopenic purpura (ITP) and warm auto-immune hemolytic anemia (AIHA) both resistant to immunosuppressive and biological therapies, not eligible for a surgical intervention because of her critical conditions. She underwent SSAE and achieved a hematologic complete response within a few days without complications. SSAE is a minimally invasive procedure to date not considered a standard option in the management of AIHA and ITP. However, following the progressive improvement of the techniques, its indications have been extended, with a reduction in morbidity and mortality compared to splenectomy in patients with critical clinical conditions. SSAE was a lifesaving therapeutic approach for our patient and it may represent a real alternative for the treatment of resistant AIHA and ITP patients not eligible for splenectomy. |
topic |
Selective splenic artery embolization, warm auto-immune hemolytic anemia,idiopathic thrombocytopenic purpura |
url |
http://www.mjhid.org/index.php/mjhid/article/view/2544 |
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