Hammerhead ribozyme activity and oligonucleotide duplex stability in mixed solutions of water and organic compounds
Nucleic acids are useful for biomedical targeting and sensing applications in which the molecular environment is different from that of a dilute aqueous solution. In this study, the influence of various types of mixed solutions of water and water-soluble organic compounds on RNA was investigated by...
Main Authors: | Shu-ichi Nakano, Yuichi Kitagawa, Daisuke Miyoshi, Naoki Sugimoto |
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Format: | Article |
Language: | English |
Published: |
Wiley
2014-01-01
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Series: | FEBS Open Bio |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2211546314000643 |
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