Preparation and activity of glycosylated acetylsalicylic acid

The glycosylated acetylsalicylic acid was prepared with bromo-α-d-galactose and acetylsalicylic acid. It indicated that the glycosylated acetylsalicylic acid had lower cytotoxicity than underivatized acetylsalicylic acid, and might selectively display anticancer activity in this situation that had e...

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Bibliographic Details
Main Authors: Gangliang Huang, Hao Cheng, Yang Liu, Jinchuan Hu
Format: Article
Language:English
Published: Elsevier 2018-02-01
Series:Saudi Pharmaceutical Journal
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S1319016417302098
Description
Summary:The glycosylated acetylsalicylic acid was prepared with bromo-α-d-galactose and acetylsalicylic acid. It indicated that the glycosylated acetylsalicylic acid had lower cytotoxicity than underivatized acetylsalicylic acid, and might selectively display anticancer activity in this situation that had enzyme or no enzyme.
ISSN:1319-0164