Toll like receptor 7 expressed by malignant cells promotes tumor progression and metastasis through the recruitment of myeloid derived suppressor cells

Toll like receptor 7 expressed by malignant cells promotes tumor progression and metastasis through the recruitment of myeloid derived suppressor cells

In non-small cell lung carcinoma (NSCLC), stimulation of toll-like receptor 7 (TLR7), a receptor for single stranded RNA, is linked to tumor progression and resistance to anticancer chemotherapy. However, the mechanism of this effect has been elusive. Here, using a murine model of lung adenocarcinom...

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Bibliographic Details
Main Authors: Marion Dajon, Kristina Iribarren, Florent Petitprez, Solenne Marmier, Audrey Lupo, Mélanie Gillard, Hanane Ouakrim, Navas Victor, Di Bartolo Vincenzo, Pierre Emmanuel Joubert, Oliver Kepp, Guido Kroemer, Marco Alifano, Diane Damotte, Isabelle Cremer
Format: Article
Language:English
Published: Taylor & Francis Group 2019-01-01
Series:OncoImmunology
Subjects:
tlr7
lung adenocarcinoma
metastasis
emt
mdsc
Online Access:http://dx.doi.org/10.1080/2162402X.2018.1505174

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