Phospholipid, arachidonate and eicosanoid signaling in schizophrenia

Phospholipid, arachidonate and eicosanoid signaling in schizophrenia

This paper reviews the potential role of arachidonic acid in the pathophysiology of schizophrenia. We discuss how abnormal levels of arachidonic acid may arise, and how dysregulation of signaling molecules derived from it have the potential to disrupt not only dopamine signaling, but numerous other...

Full description

Bibliographic Details
Main Authors:	Messamore Erik, Yao Jeffrey K.
Format:	Article
Language:	English
Published:	EDP Sciences 2016-01-01
Series:	Oilseeds and fats, crops and lipids
Subjects:	Phospholipids arachidonic acid eicosanoids niacin-induced flushing, endophenotype marker schizophrenia
Online Access:	http://dx.doi.org/10.1051/ocl/2015054

Similar Items

Phospholipid Arachidonic Acid Remodeling During Phagocytosis in Mouse Peritoneal Macrophages
by: Luis Gil-de-Gómez, et al.
Published: (2020-08-01)

Editorial: Eicosanoids in Cancer
by: Nune Markosyan, et al.
Published: (2021-09-01)

Cellular Plasmalogen Content Does Not Influence Arachidonic Acid Levels or Distribution in Macrophages: A Role for Cytosolic Phospholipase A<sub>2</sub>γ in Phospholipid Remodeling
by: Patricia Lebrero, et al.
Published: (2019-07-01)

Essential Role for Ethanolamine Plasmalogen Hydrolysis in Bacterial Lipopolysaccharide Priming of Macrophages for Enhanced Arachidonic Acid Release
by: Luis Gil-de-Gómez, et al.
Published: (2017-09-01)

Cytochrome P450 and arachidonic acid bioactivation: molecular and functional properties of the arachidonate monooxygenase
by: Jorge H. Capdevila, et al.
Published: (2000-02-01)

Fatty acid remodeling by LPCAT3 enriches arachidonate in phospholipid membranes and regulates triglyceride transport
by: Tomomi Hashidate-Yoshida, et al.
Published: (2015-04-01)

Concentrations of Proinflammatory Mediators of The Arachidonic Acid Cascade in Serum of Sheep with Natural Zearalenone Intoxication
by: Kostro Krzysztof, et al.
Published: (2012-03-01)

Arachidonate metabolism and the signaling pathway of induction of apoptosis by oxidized LDL/oxysterol
by: Sankhavaram R. Panini, et al.
Published: (2001-10-01)

Metabolism of arachidonic and adrenic acids in molecular species of gycerophospholipids in mouse brain /
by: Harder, Hubert Werner
Published: (1986)

MicroRNA involved in inflammation: Control of eicosanoid pathway
by: Meike J. Ochs, et al.
Published: (2011-07-01)

Changes in Phospholipid/Ceramide Profiles and Eicosanoid Levels in the Plasma of Rats Irradiated with UV Rays and Treated Topically with Cannabidiol
by: Wojciech Łuczaj, et al.
Published: (2021-08-01)

Deuterated Arachidonic Acids Library for Regulation of Inflammation and Controlled Synthesis of Eicosanoids: An In Vitro Study
by: Dmitry V. Chistyakov, et al.
Published: (2018-12-01)

Dysregulation of phospholipase and cyclooxygenase expression is involved in Schizophrenia
by: Xuhan Yang, et al.
Published: (2021-02-01)

Arachidonic Acid in Human Milk
by: Norman Salem, et al.
Published: (2020-02-01)

Emerging Role of Phospholipase-Derived Cleavage Products in Regulating Eosinophil Activity: Focus on Lysophospholipids, Polyunsaturated Fatty Acids and Eicosanoids
by: Eva Knuplez, et al.
Published: (2021-04-01)

ALOX5 gene variants affect eicosanoid production and response to fish oil supplementation[S]
by: Charles B. Stephensen, et al.
Published: (2011-05-01)

Dietary arachidonate in milk replacer triggers dual benefits of PGE2 signaling in LPS-challenged piglet alveolar macrophages
by: Kathleen R. Walter, et al.
Published: (2019-02-01)

Shotgun Lipidomics for the Determination of Phospholipid and Eicosanoid Profiles in Atlantic Salmon (<i>Salmo salar</i> L.) Muscle Tissue Using Electrospray Ionization (ESI)-MS/MS Spectrometric Analysis
by: JuDong Yeo, et al.
Published: (2021-02-01)

Structural characterization of oxidized phospholipid products derived from arachidonate-containing plasmenyl glycerophosphocholine
by: Nona Khaselev, et al.
Published: (2000-04-01)

Formation of eicosanoids, E2/D2 isoprostanes, and docosanoids following decapitation-induced ischemia, measured in high-energy-microwaved rat brain*
by: Santiago E. Farias, et al.
Published: (2008-09-01)

On the cellular metabolism of the click chemistry probe 19-alkyne arachidonic acid[S]
by: Philippe Pierre Robichaud, et al.
Published: (2016-10-01)

Simultaneous analyses of urinary eicosanoids and related mediators identified tetranor-prostaglandin E metabolite as a novel biomarker of diabetic nephropathy
by: Yoshifumi Morita, et al.
Published: (2021-01-01)

Neurocognitive and neurophysiological endophenotypes in schizophrenia: An overview
by: Francesco Luciano Donati, et al.
Published: (2020-12-01)

Lysophospholipid acyltransferases and leukotriene biosynthesis: intersection of the Lands cycle and the arachidonate PI cycle[S]
by: Robert C. Murphy, et al.
Published: (2019-02-01)

Increasing Dietary Linoleic Acid Does Not Increase Tissue Arachidonic Acid Content in Adults Consuming Western- Type Diets
by: Rett, Brian
Published: (2011)

Pellagra in patient with schizophrenia: a case report and review of literature
by: Jaya Madhuri Mothukuri, et al.
Published: (2013-01-01)

Choline Glycerophospholipid-Derived Prostaglandins Attenuate TNFα Gene Expression in Macrophages via a cPLA<sub>2</sub>α/COX-1 Pathway
by: Alma M. Astudillo, et al.
Published: (2021-02-01)

Arachidonic Acid Metabolites in Cardiovascular and Metabolic Diseases
by: Thomas Sonnweber, et al.
Published: (2018-10-01)

Eicosanoids in skin inflammation.
by: Nicolaou, Anna
Published: (2012)

Marked elevations in pro-inflammatory polyunsaturated fatty acid metabolites in females with irritable bowel syndrome
by: Gerard Clarke, et al.
Published: (2010-05-01)

Phospholipase A2 structure/function, mechanism, and signaling1
by: John E. Burke, et al.
Published: (2009-01-01)

Cytochrome P450-derived epoxyeicosatrienoic acids and coronary artery disease in humans: a targeted metabolomics study
by: Akinyemi Oni-Orisan, et al.
Published: (2016-01-01)

Dietary Polyunsaturated Fatty Acids and Inflammation: The Role of Phospholipid Biosynthesis
by: Lorraine M. Sordillo, et al.
Published: (2013-10-01)

A new era of secreted phospholipase A2
by: Makoto Murakami, et al.
Published: (2015-07-01)

SKINREMS—A New Method for Assessment of the Niacin Skin Flush Test Response in Schizophrenia
by: Hanna Karakula-Juchnowicz, et al.
Published: (2020-06-01)

Long-chain acyl-CoA synthetase isoforms differ in preferences for eicosanoid species and long-chain fatty acids[S]
by: Eric L. Klett, et al.
Published: (2017-05-01)

Alterations in Lipoxygenase and Cyclooxygenase-2 Catalytic Activity and mRNA Expression in Prostate Carcinoma
by: Scott B. Shappell, et al.
Published: (2001-01-01)

Pulmonary epithelial cancer cells and their exosomes metabolize myeloid cell-derived leukotriene C4 to leukotriene D4
by: Ana Lukic, et al.
Published: (2016-09-01)

Parenteral Fish-Oil Containing Lipid Emulsions Limit Initial Lipopolysaccharide-Induced Host Immune Responses in Preterm Pigs
by: William Yakah, et al.
Published: (2021-01-01)

Calcium-independent phospholipases A2 and their roles in biological processes and diseases
by: Sasanka Ramanadham, et al.
Published: (2015-09-01)