Eosinophils and megakaryocytes support the early growth of murine MOPC315 myeloma cells in their bone marrow niches.

Eosinophils and megakaryocytes support the early growth of murine MOPC315 myeloma cells in their bone marrow niches.

Multiple myeloma is a bone marrow plasma cell tumor which is supported by the external growth factors APRIL and IL-6, among others. Recently, we identified eosinophils and megakaryocytes to be functional components of the micro-environmental niches of benign bone marrow plasma cells and to be import...

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Bibliographic Details
Main Authors: David Wong, Oliver Winter, Christina Hartig, Svenja Siebels, Martin Szyska, Benjamin Tiburzy, Lingzhang Meng, Upasana Kulkarni, Anke Fähnrich, Kurt Bommert, Ralf Bargou, Claudia Berek, Van Trung Chu, Bjarne Bogen, Franziska Jundt, Rudolf Armin Manz
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4182881?pdf=render

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