The Spectrum of Histopathological Lesions in Scarring Alopecia: A Prospective Study

• Main Authors: Mahesh Kumar U., Balasaheb Ramling Yelikar
• Format: Article
• Language: English
• Published: JCDR Research and Publications Private Limited 2013-07-01
• Series: Journal of Clinical and Diagnostic Research
• Subjects: scarring alopecia; lupus erythematosus; a congenital absence of the skin
• Online Access: https://jcdr.net/articles/PDF/3131/26%20-%205138_PF1(M)_E(C)_F(T)_F1(M)_F1(T)_FA(T)_PF1(PUH)_1.pdf
• ISSN: 2249-782X; 0973-709X

Introduction: The aim of the article was to study the histopathological features of various lesions of Scarring Alopecia (SA) and to classify Primary SA on the basis of the predominant type of inflammatory cell component. Scarring or cicatricial alopecias are those that are produced as a result of the malformation, damage or destruction of the pilosebaceous follicles, which are replaced by cicatricial tissue, in such a way that they cannot again produce hair. Material and Methods: This prospective study included 32 biopsy – proven cases of SA, who had attended our hospital. Primary SA was classified according to the North American Hair Research Society. The informed consents of the subjects and the institutional ethical clearance was obtained for the study. The SPSS, version 14 software was used to analyse the data. Frequencies and percentages were used to describe the data. Results: During the study period, 32 cases of scarring alopecia were diagnosed, of which 24 were primary SA and 8 were secondary SA. Among the primary SA, there were 23 cases of lymphocyte associated primary scarring alopecias, of which, 19 of lupus erythematosus, 3 of lichen planopilaris (LPP) and one case of non specific SA. 1 case of neutrophil associated primary scarring (folliculitis decalvans) was also noted and among the secondary SA, there were 4 cases of morphea and 1 case each of lupus vulgaris, congenital absence of skin, burn and sarcoidosis. Conclusion: To conclude, histopathology is a dependable tool for identifying the underlying cause in scarring alopecia, which is helpful for an early diagnosis and treatment.