| Summary: | A series of <em>N</em>-substituted 5-chloro-6-phenylpyridazin-3(2<em>H</em>)-one derivatives were synthesized based on our previous work; all compounds were characterized by spectral data and tested for <em>in vitro</em> insecticidal activity against <em>Plutella xylostella</em>. The results showed that the synthesized pyridazin-3(2<em>H</em>)-one compounds possessed good insecticidal activities, especially the compounds <strong>4b</strong>, <strong>4d</strong>, and <strong>4h </strong>which showed > 90% activity at 100 mg/L. The structure-activity relationships (SAR) for these compounds were also discussed.
|
|---|
