Epigenetic crosstalk between hypoxia and tumor driven by HIF regulation
Abstract Hypoxia is the major influence factor in physiological and pathological courses which are mainly mediated by hypoxia-inducible factors (HIFs) in response to low oxygen tensions within solid tumors. Under normoxia, HIF signaling pathway is inhibited due to HIF-α subunits degradation. However...
Main Authors: | Tiansheng Li, Chao Mao, Xiang Wang, Ying Shi, Yongguang Tao |
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Format: | Article |
Language: | English |
Published: |
BMC
2020-10-01
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Series: | Journal of Experimental & Clinical Cancer Research |
Subjects: | |
Online Access: | http://link.springer.com/article/10.1186/s13046-020-01733-5 |
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