Distinct Transcriptional and Alternative Splicing Signatures of Decidual CD4+ T Cells in Early Human Pregnancy

Distinct Transcriptional and Alternative Splicing Signatures of Decidual CD4+ T Cells in Early Human Pregnancy

Decidual CD4+ T (dCD4 T) cells are crucial for the maternal-fetal immune tolerance required for a healthy pregnancy outcome. However, their molecular and functional characteristics are not well elucidated. In this study, we performed the first analysis of transcriptional and alternative splicing (AS...

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Bibliographic Details
Main Authors: Weihong Zeng, Zhicui Liu, Xinmei Liu, Siming Zhang, Asma Khanniche, Ying Zheng, Xiaoling Ma, Tiantian Yu, Fuju Tian, Xiao-Rui Liu, Jianxia Fan, Yi Lin
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-06-01
Series:Frontiers in Immunology
Subjects:
decidual CD4+ T cells
early human pregnancy
transcriptome
alternative splicing
high-throughput mRNA sequencing
Online Access:http://journal.frontiersin.org/article/10.3389/fimmu.2017.00682/full

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