Towards Clinical Application of Neurotrophic Factors to the Auditory Nerve; Assessment of Safety and Efficacy by a Systematic Review of Neurotrophic Treatments in Humans

Towards Clinical Application of Neurotrophic Factors to the Auditory Nerve; Assessment of Safety and Efficacy by a Systematic Review of Neurotrophic Treatments in Humans

Animal studies have evidenced protection of the auditory nerve by exogenous neurotrophic factors. In order to assess clinical applicability of neurotrophic treatment of the auditory nerve, the safety and efficacy of neurotrophic therapies in various human disorders were systematically reviewed. Outc...

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Bibliographic Details
Main Authors: Aren Bezdjian, Véronique J. C. Kraaijenga, Dyan Ramekers, Huib Versnel, Hans G. X. M. Thomeer, Sjaak F. L. Klis, Wilko Grolman
Format: Article
Language:English
Published: MDPI AG 2016-11-01
Series:International Journal of Molecular Sciences
Subjects:
neurotrophin
growth factor
clinical trial
neurodegenerative disorders
inner ear
peripheral nervous system
translational medicine
Online Access:http://www.mdpi.com/1422-0067/17/12/1981

Internet

http://www.mdpi.com/1422-0067/17/12/1981

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