Establishment of an Endogenous Clostridium difficile Rat Infection Model and Evaluation of the Effects of Clostridium butyricum MIYAIRI 588 Probiotic Strain
Clostridium difficile is well known as an agent responsible for pseudomembranous colitis and antibiotic-associated diarrhea. The hamster model utilizing an oral route for infection of C. difficile has been considered to be the standard model for analysis of C. difficile infection (CDI) but this mode...
Main Authors: | Kentaro Oka, Takako Osaki, Tomoko Hanawa, Satoshi Kurata, Emi Sugiyama, Motomichi Takahashi, Mamoru Tanaka, Haruhiko Taguchi, Shigeru Kamiya |
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Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2018-06-01
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Series: | Frontiers in Microbiology |
Subjects: | |
Online Access: | https://www.frontiersin.org/article/10.3389/fmicb.2018.01264/full |
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